Multiscale mechanobiology in brain physiology and diseases

A Procès, M Luciano, Y Kalukula, L Ris… - Frontiers in Cell and …, 2022 - frontiersin.org
Increasing evidence suggests that mechanics play a critical role in regulating brain function
at different scales. Downstream integration of mechanical inputs into biochemical signals …

Atomic force microscopy in characterizing cell mechanics for biomedical applications: A review

M Li, D Dang, L Liu, N Xi, Y Wang - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Cell mechanics is a novel label-free biomarker for indicating cell states and pathological
changes. The advent of atomic force microscopy (AFM) provides a powerful tool for …

Cells nanomechanics by atomic force microscopy: focus on interactions at nanoscale

G Zhou, B Zhang, G Tang, XF Yu… - Advances in Physics …, 2021 - Taylor & Francis
Nanomechanics of cytoskeleton is deeply involved in physiology and regulation of cell
behavior. Atomic Force Microscopy has been extensively used for quantitative …

Mechanical and structural comparison between primary tumor and lymph node metastasis cells in colorectal cancer

V Palmieri, D Lucchetti, A Maiorana, M Papi… - Soft matter, 2015 - pubs.rsc.org
SW480 and SW620 colon carcinoma cell lines derive from primary tumour and lymph-node
metastasis of the same patient, respectively. For this reason, these cells represent an ideal …

Atomic force microscopy and pharmacology: from microbiology to cancerology

F Pillet, L Chopinet, C Formosa, É Dague - Biochimica et Biophysica Acta …, 2014 - Elsevier
Abstract Background Atomic Force Microscopy (AFM) has been extensively used to study
biological samples. Researchers take advantage of its ability to image living samples to …

Large colloidal probes for atomic force microscopy: Fabrication and calibration issues

M Chighizola, L Puricelli, L Bellon… - Journal of Molecular …, 2021 - Wiley Online Library
Atomic force microscopy (AFM) is a powerful tool to investigate interaction forces at the micro
and nanoscale. Cantilever stiffness, dimensions and geometry of the tip can be chosen …

Investigation of adhesion and mechanical properties of human glioma cells by single cell force spectroscopy and atomic force microscopy

L Andolfi, E Bourkoula, E Migliorini, A Palma, A Pucer… - PLoS one, 2014 - journals.plos.org
Active cell migration and invasion is a peculiar feature of glioma that makes this tumor able
to rapidly infiltrate into the surrounding brain tissue. In our recent work, we identified a novel …

Native extracellular matrix probes to target patient-and tissue-specific cell–microenvironment interactions by force spectroscopy

H Holuigue, L Nacci, P Di Chiaro, M Chighizola… - Nanoscale, 2023 - pubs.rsc.org
Atomic Force Microscopy (AFM) is successfully used for the quantitative investigation of the
cellular mechanosensing of the microenvironment. To this purpose, several force …

Nanoscale imaging and force probing of biomolecular systems using atomic force microscopy: from single molecules to living cells

M Li, D Dang, N Xi, Y Wang, L Liu - Nanoscale, 2017 - pubs.rsc.org
Due to the lack of adequate tools for observation, native molecular behaviors at the
nanoscale have been poorly understood. The advent of atomic force microscopy (AFM) …

Evidence use in E-cigarettes debates: scientific showdowns in a 'wild west'of research

KE Smith, T Ikegwuonu, H Weishaar, S Hilton - BMC Public Health, 2021 - Springer
Background Against a backdrop of declining tobacco use, e-cigarette markets are growing.
The UK now has a higher percentage of e-cigarette users than any other European country …