Tuberculosis remains a global health problem, with an estimated 10.4 million cases and 1.8
million deaths resulting from the disease in 2015. The most lethal and disabling form of …

Tuberculous meningitis is especially common in young children and people with untreated
HIV infection, and it kills or disables roughly half of everyone affected. Childhood disease …

Background Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency
syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; …

Cryptococcal meningitis is common in sub-Saharan Africa. Given the need for data for a
rapid, point-of-care cryptococcal antigen (CRAG) lateral flow immunochromatographic assay …

Survival in people infected with HIV has improved because of an increasingly powerful array
of antiretroviral treatments, but neurological symptoms due to comorbid conditions, including …

Tropical mycoses vary from the commonplace to the rare and exotic but they are seen
regularly even as imported conditions and it is important to consider the diagnosis, where …

Infectious meningitis may be due to bacterial, mycobacterial, fungal or viral agents.
Diagnosis of meningitis must take into account numerous items of patient history and …

Meningitis remains a worldwide problem, and rapid diagnosis is essential to optimize
survival. We evaluated the utility of a multiplex PCR test in differentiating possible etiologies …

Background. Cryptococcus neoformans is the most common cause of adult meningitis in sub-
Saharan Africa. The cryptococcal antigen (CRAG) lateral flow assay (LFA) has simplified …

Abstract Background. The Cryptococcus neoformans polysaccharide capsule is a well-
characterized virulence factor with immunomodulatory properties. The organism and/or shed …