Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

In an organic chemistry, largest families of organic compounds are belongs in the
heterocyclic compounds. In our daily life important of heterocyclic compounds are of very …

A series of new coumarin-based 1, 2, 4-triazole derivatives were designed, synthesized and
evaluated for their antimicrobial activities in vitro against four Gram-positive bacteria …

In the present study, we have synthesized 2-(substituted phenyl)-1H-imidazole (1–12) and
(substituted phenyl)-[2-(substituted phenyl)-imidazol-1-yl]-methanone (13–26) analogues …

Imidazole nucleus is a constituent of many bioactive heterocyclic compounds that are of
wide interest because of their diverse biological and clinical applications. This created …

In the present work, 1-(5-methyl-2-phenyl-1H-imidazol-4-yl) ethanone 1 was prepared and
used as a precursor for the synthesis of new thiazole, arylidiene and coumarin derivatives …

In this study, we investigated in vitro the potential of Trichoderma harzianum to produce
bioactive secondary metabolites that can be used as alternatives to synthetic compounds …

Owing to the urgent need for therapeutic interventions against the SARS-coronavirus 2
(SARS-CoV-2) pandemic, we employed an in silico approach to evaluate the SARS-CoV-2 …

The antifungals that are in current clinical practice have a high occurrence of a side effect
and multidrug resistance (MDR). Researchers across the globe are trying to develop a …

Imidazoles are one of the most promising and vigorously pursued areas of contemporary
antifungal chemotherapy depicting broad spectrum and potent activity. They have relatively …