Boosting myocardial resistance to acute as well as chronic ischemic damage would
ameliorate the detrimental effects of numerous cardiac pathologies and reduce the …

Fibroblast growth factor 21 is an endocrine factor, secreted mainly by the liver, that exerts
metabolic actions that favour glucose metabolism. Its role in the heart is unknown. Here we …

The identification of collateral artery growth (arteriogenesis) as the only mechanism to
compensate for the loss of an occluded artery forced us to define the mechanisms …

Growth of new blood vessels (angiogenesis), required for all tumor growth, is stimulated by
the expression of vascular endothelial growth factor (VEGF). VEGF is up-regulated in all …

One of the trophic factors that has been implicated in initiating or facilitating growth in
response to increased mechanical stress in several tissues and cell types is basic fibroblast …

Aims Proliferation of mammalian cardiomyocytes stops during the first weeks after birth,
preventing the heart from regenerating after injury. Recently, several studies have indicated …

Mitogenic stimulation of cardiomyocytes is associated with decreased gap junction coupling
and protein kinase C (PKC)-mediated phosphorylation of the gap junction protein …

Abstract Fibroblast growth factor 2 (FGF-2), a multifunctional polypeptide that affects cell
growth and differentiation and becomes upregulated by stress, is expressed as AUG …

Increasing evidence suggests that fibroblast growth factors (FGFs) are neurotrophic in GnRH
neurons. However, the extent to which FGFs are involved in establishing a functional GnRH …

Basic fibroblast growth factor (FGF-2) plays a vital role in the growth and differentiation of
cardiac myocytes. It exists in high and low molecular weight forms because of the use of …