Liquid crystal-based biosensors as lab-on-chip tools: Promising for future on-site detection test kits

Z Khoshbin, K Abnous, SM Taghdisi… - TrAC Trends in Analytical …, 2021 - Elsevier
Advancement in liquid crystal (LC) technology has achieved an impressive development of
the sensing platforms. The long-range orientational order of LC molecules provides the …

Bile acids and gestation

S McIlvride, PH Dixon, C Williamson - Molecular aspects of medicine, 2017 - Elsevier
There are numerous profound maternal physiological changes that occur from conception
onwards and adapt throughout gestation in order to support a healthy pregnancy. By the …

Roles of PPARγ/NF-κB signaling pathway in the pathogenesis of intrahepatic cholestasis of pregnancy

Y Zhang, L Hu, Y Cui, Z Qi, X Huang, L Cai, T Zhang… - PloS one, 2014 - journals.plos.org
Background Intrahepatic cholestasis of pregnancy (ICP) is the most prevalent pregnancy
specific liver disease. However, the pathogenesis and etiology of ICP is poorly understood …

Intrahepatic cholestasis of pregnancy: insights into pathogenesis and advances in omics studies

M Tang, L Xiong, J Cai, J Fu, H Liu, Y Ye, L Yang… - Hepatology …, 2024 - Springer
Intrahepatic cholestasis of pregnancy (ICP) is the most common pregnancy-specific liver
disease. It is characterized by pruritus, abnormal liver function and elevated total bile acid …

Bile acids and bilirubin effects on osteoblastic gene profile. Implications in the pathogenesis of osteoporosis in liver diseases

S Ruiz-Gaspà, N Guañabens, S Jurado, M Dubreuil… - Gene, 2020 - Elsevier
Osteoporosis in advanced cholestatic and end-stage liver disease is related to low bone
formation. Previous studies have demonstrated the deleterious consequences of lithocholic …

[HTML][HTML] Effect of histone deacetylase HDAC3 on cytokines IL-18, IL-12 and TNF-α in patients with intrahepatic cholestasis of pregnancy

Y Shao, J Chen, J Zheng, CR Liu - Cellular Physiology and …, 2017 - karger.com
Background/aims: The pathogenesis of intrahepatic cholestasis of pregnancy (ICP) is poorly
understood. Objective: This study aimed to explore the possible effect of HDAC3 (histone …

Liquid crystals-based sensor for the detection of lithocholic acid coupled with competitive host-guest inclusion

H Ma, Q Kang, T Wang, J Xiao, L Yu - Colloids and Surfaces B …, 2019 - Elsevier
A simple, low-cost and label-free strategy for detecting lithocholic acid (LCA) was designed
at the liquid crystals (LCs)/aqueous interface via competitive host-guest inclusion. In this …

[HTML][HTML] SWATH proteomics analysis of placental tissue with intrahepatic cholestasis of pregnancy

Y Jiang, X Yin, Q Xu, X Tang, H Zhang, X Cao, J Lin… - Placenta, 2023 - Elsevier
Introduction Intrahepatic cholestasis of pregnancy (ICP) usually occurs in the second and
third trimesters. The disease's etiology and diagnostic criteria are currently unknown. Based …

Lithocholic acid activates mTOR signaling inducing endoplasmic reticulum stress in placenta during intrahepatic cholestasis of pregnancy

S Chao, L Xiaojun, W Haizhen, F Ludi, L Shaozhen… - Life sciences, 2019 - Elsevier
Aims Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific disorder, which
increases risks of adverse fetal outcomes. However, the pathophysiology is not fully …

Serum profiles of inflammatory cytokines associated with intrahepatic cholestasis of pregnancy

S Huang, Y Liu, N Guo, X Liu, G Li… - The Journal of Maternal …, 2022 - Taylor & Francis
Background The pathogenesis of intrahepatic cholestasis of pregnancy (ICP) is not clear,
and some researchers have compared the differences in serum levels of inflammatory …