Lifestyle and genetic background are well known risk factors of cardiovascular disease
(CVD). A third contributing factor is suboptimal fetal development, due to nutrient or oxygen …

Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …

Hypertension remains the leading cause of disease burden worldwide. Hypertension can
originate in the early stages of life. A growing body of evidence suggests that oxidative …

In this study, we examine whether Clitoria ternatea Linn.(CT) can prevent Nω-nitro-L-
arginine methyl ester hydrochloride (L-NAME)-induced cardiac and vascular dysfunction in …

Cardiovascular disease (CVD) presents a global health burden, despite recent advances in
management. CVD can originate from early life by so-called “developmental origins of …

Intrauterine growth restriction, a common consequence of prenatal hypoxia, is a leading
cause of fetal morbidity and mortality with a significant impact on population health. Hypoxia …

The worldwide increase in metabolic diseases has urged the scientific community to
improve our understanding about the mechanisms underlying its cause and effects. A well …

Resveratrol (RSV) has been reported to have potential beneficial effects in the complicated
pregnancy. Various pregnancy complications lead to a suboptimal in utero environment that …

Galangin is a natural flavonoid. In this study, we evaluated whether galangin could alleviate
signs of metabolic syndrome (MS) and cardiac abnormalities in rats receiving a high-fat (HF) …

Scope Prenatal stress is closely associated with poor health outcomes for offspring, yet the
specific mechanisms and effective interventions remain limited. Methods and Results In the …