[HTML][HTML] Imprinting at the KBTBD6 locus involves species-specific maternal methylation and monoallelic expression in livestock animals

J Ahn, IS Hwang, MR Park, S Hwang, K Lee - Journal of Animal Science …, 2023 - Springer
Background The primary differentially methylated regions (DMRs) which are maternally
hypermethylated serve as imprinting control regions (ICRs) that drive monoallelic gene …

[HTML][HTML] Loss of Monoallelic Expression of IGF2 in the Adult Liver Via Alternative Promoter Usage and Chromatin Reorganization

J Ahn, J Lee, DH Kim, IS Hwang, MR Park… - Frontiers in …, 2022 - frontiersin.org
In mammals, genomic imprinting operates via gene silencing mechanisms. Although
conservation of the imprinting mechanism at the H19/IGF2 locus has been generally …

The Landscape of Genomic Imprinting at the Porcine SGCE/PEG10 Locus from Methylome and Transcriptome of Parthenogenetic Embryos

J Ahn, IS Hwang, MR Park, IC Cho… - G3: Genes, Genomes …, 2020 - academic.oup.com
In mammals, imprinted genes often exist in the form of clusters in specific chromosome
regions. However, in pigs, genomic imprinting of a relatively few genes and clusters has …

[HTML][HTML] Developmental and degenerative characterization of porcine parthenogenetic fetuses during early pregnancy

IS Hwang, MR Park, HS Lee, TU Kwak, HY Son… - Animals, 2020 - mdpi.com
Simple Summary To increase the early implantation rate, oocytes and zygotes have been
subjected to various artificial stimulations before and/or after in vitro fertilization, nuclear …

[HTML][HTML] Genomic Imprinting at the Porcine DIRAS3 Locus

J Ahn, IS Hwang, MR Park, S Hwang, K Lee - Animals, 2021 - mdpi.com
Simple Summary DNA methylation associated with one of the two alleles from parents is an
important mechanism that causes a silencing of that allele, leading to expression of another …

[HTML][HTML] Conservation and divergence of canonical and non-canonical imprinting in murids

J Richard Albert, T Kobayashi, A Inoue… - Genome biology, 2023 - Springer
Background Genomic imprinting affects gene expression in a parent-of-origin manner and
has a profound impact on complex traits including growth and behavior. While the rat is …

Lineage-specific genomic imprinting in the ZNF791 locus

J Ahn, IS Hwang, MR Park, M Rosa-Velazquez, IC Cho… - bioRxiv, 2024 - biorxiv.org
Background: Genomic imprinting is the primary epigenetic phenomenon that results in
parent-of-origin effects on mammalian development and growth. Research on genomic …

The AIRN lncRNA is imprinted and paternally expressed in pigs

J Ahn, IS Hwang, MR Park, S Hwang… - Journal of Animal …, 2023 - academic.oup.com
Genomic imprinting plays critical roles during the development of mammalian species and
underlying epigenetic mechanisms frequently involve long non-coding RNAs (lncRNAs) …

[HTML][HTML] Genomic Imprinting at the Porcine PLAGL1 Locus and the Orthologous Locus in the Human

J Ahn, IS Hwang, MR Park, S Hwang, K Lee - Genes, 2021 - mdpi.com
Implementation of genomic imprinting in mammals often results in cis-acting silencing of a
gene cluster and monoallelic expression, which are important for mammalian growth and …

Comparative maternal protein profiling of mouse biparental and uniparental embryos

F Chen, B Ma, Y Lin, X Luo, T Xu, Y Zhang… - …, 2022 - academic.oup.com
Background Maternal proteins have important roles during early embryonic development.
However, our understanding of maternal proteins is still very limited. The integrated analysis …