Blood vessels are critical to deliver oxygen and nutrients to all of the tissues and organs
throughout the body. The blood vessels that vascularize the central nervous system (CNS) …

Blood vessels are critical to deliver oxygen and nutrients to tissues and organs throughout
the body. The blood vessels that vascularize the central nervous system (CNS) possess …

The CNS is endowed with an elaborated response repertoire termed'neuroinflammation',
which enables it to cope with pathogens, toxins, traumata and degeneration. On the basis of …

The blood–brain barrier (BBB) is formed by tightly connected cerebrovascular endothelial
cells, but its normal function also depends on paracrine interactions between the brain …

The specifically regulated restrictive permeability barrier to cells and molecules is the most
important feature of the blood–brain barrier (BBB). The aim of this review was to summarize …

Three different barriers are formed between the cerebrovascular and the brain parenchyma:
the blood-brain barrier (BBB), the blood-cerebrospinal fluid barrier (BCSFB), and the …

The blood–brain barrier is a highly selective anatomical and functional interface allowing a
unique environment for neuro-glia networks. Blood–brain barrier dysfunction is common in …

The majority of brain metastases originate from lung cancer, breast cancer and malignant
melanoma. In order to reach the brain, parenchyma metastatic cells have to transmigrate …

Over the last 15 years, attention has been focused on dysfunction of the cerebral vasculature
and inflammation as important players in epileptogenic processes, with a specific emphasis …

Glutamate serves as the dominant central nervous system (CNS) excitatory neurotransmitter,
in part by activating N-methyl-D-aspartate receptors (NMDARs). While the structure, function …