Nanoemulgel: a novel nano carrier as a tool for topical drug delivery

MR Donthi, SR Munnangi, KV Krishna, RN Saha… - Pharmaceutics, 2023 - mdpi.com
Nano-emulgel is an emerging drug delivery system intended to enhance the therapeutic
profile of lipophilic drugs. Lipophilic formulations have a variety of limitations, which includes …

An overview of nanoemulgels for bioavailability enhancement in inflammatory conditions via topical delivery

DK Lal, B Kumar, AS Saeedan, MN Ansari - Pharmaceutics, 2023 - mdpi.com
The anti-inflammatory drugs that are generally available possess the disadvantage of
hydrophobicity, which leads to poor permeability and erratic bioavailability. Nanoemulgels …

[HTML][HTML] Development and characterization of a poloxamer hydrogel composed of human mesenchymal stromal cells (hMSCs) for reepithelization of skin injuries

C Galocha-León, C Antich, A Voltes-Martínez… - International Journal of …, 2023 - Elsevier
Wound healing is a natural physiological reaction to tissue injury. Hydrogels show attractive
advantages in wound healing not only due to their biodegradability, biocompatibility and …

Hydroxypropyl methylcellulose bioadhesive hydrogels for topical application and sustained drug release: the effect of polyvinylpyrrolidone on the physicomechanical …

P Pan, D Svirskis, GIN Waterhouse, Z Wu - Pharmaceutics, 2023 - mdpi.com
Hydrogels are homogeneous three-dimensional polymeric networks capable of holding
large amounts of water and are widely used in topical formulations. Herein, the …

Mucoadhesive drug delivery systems: a promising non-invasive approach to bioavailability enhancement. Part I: biophysical considerations

R Kulkarni, S Fanse, DJ Burgess - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Mucoadhesive drug delivery systems (MDDS) are specifically designed to
interact and bind to the mucosal layer for localized, prolonged, and/or targeted drug delivery …

Self-assembly mucoadhesive beads of κ-carrageenan/sericin for indomethacin oral extended release

WT Vieira, JSR Viegas, MGC da Silva… - International Journal of …, 2024 - Elsevier
Oral drug administration, especially when composed of mucoadhesive delivery systems, has
been a research trend due to increased residence time and contact with the mucosa …

Technological aspects and evaluation methods for polymer matrices as dental drug carriers

D Kida, T Konopka, K Jurczyszyn, B Karolewicz - Biomedicines, 2023 - mdpi.com
The development of polymer matrices as dental drug carriers takes into account the
following technological aspects of the developed formulations: the composition and the …

Expanding the Manufacturing Approaches for Gastroretentive Drug Delivery Systems with 3D Printing Technology

IR Turac, A Porfire, S Iurian, AG Crișan, T Casian… - Pharmaceutics, 2024 - mdpi.com
Gastroretentive drug delivery systems (GRDDSs) have gained substantial attention in the
last 20 years due to their ability to retain the drug in the stomach for an extended time, thus …

In vitro Models for Predicting Bioadhesion Fracture Strength to Ex Vivo Animal Buccal Tissue

VS Rahamim, D Patel, E Drori, S Coopersmith… - Small, 2024 - Wiley Online Library
Commitment to the 3Rs principle (Replacement, Reduction, and Refinement) led to the
development of a cell‐based system to measure buccal bioadhesion in vitro and replace the …

Formulation and evaluation of ion-triggered in situ gel for effective ocular delivery of ciprofloxacin HCl and olopatadine HCl in combination

DA Shaikh, MM Momin - Drug Delivery Letters, 2024 - ingentaconnect.com
Background: Ocular in situ gels (ISG) are an adequate substitute to overcome the pitfalls of
conventional eye drops as they acquaintance the advantages of solutions, including …