Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative

DP Veitch, MW Weiner, PS Aisen, LA Beckett… - Alzheimer's & …, 2019 - Elsevier
Introduction The overall goal of the Alzheimer's Disease Neuroimaging Initiative (ADNI) is to
validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI is a multisite …

Abnormal white matter changes in Alzheimer's disease based on diffusion tensor imaging: A systematic review

Y Chen, Y Wang, Z Song, Y Fan, T Gao… - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) is a degenerative neurological disease in elderly individuals.
Subjective cognitive decline (SCD), mild cognitive impairment (MCI) and further …

Gradual disturbances of the amplitude of low-frequency fluctuations (ALFF) and fractional ALFF in Alzheimer spectrum

L Yang, Y Yan, Y Wang, X Hu, J Lu, P Chan… - Frontiers in …, 2018 - frontiersin.org
Background: Alzheimer's disease (AD) is a common neurodegenerative disease in which
the brain undergoes alterations for decades before symptoms become obvious. Subjective …

Predicting MCI to AD conversation using integrated sMRI and rs-fMRI: machine learning and graph theory approach

T Zhang, Q Liao, D Zhang, C Zhang, J Yan… - Frontiers in Aging …, 2021 - frontiersin.org
Background Graph theory and machine learning have been shown to be effective ways of
classifying different stages of Alzheimer's disease (AD). Most previous studies have only …

Integrating across neuroimaging modalities boosts prediction accuracy of cognitive ability

J Rasero, AI Sentis, FC Yeh… - PLoS computational …, 2021 - journals.plos.org
Variation in cognitive ability arises from subtle differences in underlying neural architecture.
Understanding and predicting individual variability in cognition from the differences in brain …

High-order functional redundancy in ageing explained via alterations in the connectome in a whole-brain model

M Gatica, F E. Rosas, P AM Mediano… - PLoS computational …, 2022 - journals.plos.org
The human brain generates a rich repertoire of spatio-temporal activity patterns, which
support a wide variety of motor and cognitive functions. These patterns of activity change …

An ensemble learning approach based on diffusion tensor imaging measures for Alzheimer's disease classification

E Lella, A Pazienza, D Lofu, R Anglani, F Vitulano - Electronics, 2021 - mdpi.com
Recent advances in neuroimaging techniques, such as diffusion tensor imaging (DTI),
represent a crucial resource for structural brain analysis and allow the identification of …

Structure–function multi‐scale connectomics reveals a major role of the fronto‐striato‐thalamic circuit in brain aging

P Bonifazi, A Erramuzpe, I Diez… - Human Brain …, 2018 - Wiley Online Library
Physiological aging affects brain structure and function impacting morphology, connectivity,
and performance. However, whether some brain connectivity metrics might reflect the age of …

The effect of cognitive intervention on cognitive function in older adults with Alzheimer's disease: A systematic review and meta-analysis

YY Wang, L Yang, J Zhang, XT Zeng, Y Wang… - Neuropsychology …, 2022 - Springer
Cognitive intervention includes cognitive stimulation, cognitive training, and cognitive
rehabilitation. This systematic review was performed to re-assess the efficacy of cognitive …

[HTML][HTML] Connectome-wide network analysis of white matter connectivity in Alzheimer's disease

C Ye, S Mori, P Chan, T Ma - NeuroImage: Clinical, 2019 - Elsevier
A multivariate analytical strategy may pinpoint the structural connectivity patterns associated
with Alzheimer's disease (AD) pathology in connectome-wide association studies. Diffusion …