The neurotrophins and their receptors: structure, function, and neuropathology
LM Maness, AJ Kastin, JT Weber, WA Banks… - Neuroscience & …, 1994 - Elsevier
The neurotrophins are a family of polypeptides that promote differentiation and survival of
select peripheral and central neurons. Nerve growth factor, brain-derived neurotrophic …
select peripheral and central neurons. Nerve growth factor, brain-derived neurotrophic …
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor
Nerve growth factor (NGF) interacts with two different low-affinity receptors that can be
distinguished by affinity crosslinking. Reconstitution experiments by membrane fusion and …
distinguished by affinity crosslinking. Reconstitution experiments by membrane fusion and …
Expression and structure of the human NGF receptor
The nucleotide sequence for the human nerve growth factor (NGF) receptor has been
determined. The 3.8 kb receptor mRNA encodes a 427 amino acid protein containing a 28 …
determined. The 3.8 kb receptor mRNA encodes a 427 amino acid protein containing a 28 …
Nerve growth factor revisited
RA Bradshaw, TL Blundell, R Lapatto… - Trends in biochemical …, 1993 - Elsevier
Recent studies on nerve growth factor have revealed important new insights into the
structure, function and evolution of this prototypical neurotrophic factor. Some of its features …
structure, function and evolution of this prototypical neurotrophic factor. Some of its features …
Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors
T Wehrman, X He, B Raab, A Dukipatti, H Blau… - Neuron, 2007 - cell.com
Nerve growth factor engages two structurally distinct transmembrane receptors, TrkA and
p75, which have been proposed to create a" high-affinity" NGF binding site through …
p75, which have been proposed to create a" high-affinity" NGF binding site through …
Gene transfer and molecular cloning of the human NGF receptor
MV Chao, MA Bothwell, AH Ross, H Koprowski… - Science, 1986 - science.org
Nerve growth factor (NGF) and its receptor are important in the development of cells derived
from the neural crest. Mouse L cell transformants have been generated that stably express …
from the neural crest. Mouse L cell transformants have been generated that stably express …
[HTML][HTML] The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells
C Yeaman, AH Le Gall, AN Baldwin… - The Journal of cell …, 1997 - ncbi.nlm.nih.gov
Delivery of newly synthesized membrane-spanning proteins to the apical plasma membrane
domain of polarized MDCK epithelial cells is dependent on yet unidentified sorting signals …
domain of polarized MDCK epithelial cells is dependent on yet unidentified sorting signals …
The biological functions and signaling mechanisms of the p75 neurotrophin receptor
BR Kraemer, SO Yoon, BD Carter - Neurotrophic factors, 2014 - Springer
The p75 neurotrophin receptor (p75 NTR) regulates a wide range of cellular functions,
including programmed cell death, axonal growth and degeneration, cell proliferation …
including programmed cell death, axonal growth and degeneration, cell proliferation …
Characterization of nerve growth factor receptor in neural crest tumors using monoclonal antibodies.
AH Ross, P Grob, M Bothwell… - Proceedings of the …, 1984 - National Acad Sciences
The nerve growth factor (NGF) receptor was characterized by using a new series of anti-
receptor monoclonal antibodies (MAbs). These MAbs (i) showed significantly greater …
receptor monoclonal antibodies (MAbs). These MAbs (i) showed significantly greater …
Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer
Revised Manuscript Received January 17, 1995® abstract: The development and
sustenance of specific neuronal populations in the peripheral and central nervous systems …
sustenance of specific neuronal populations in the peripheral and central nervous systems …