Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …

Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …

Genome editing holds great potential for cancer treatment due to the ability to precisely
inactivate or repair cancer-related genes. However, delivery of CRISPR/Cas to solid tumours …

BACKGROUND Uterine leiomyoma (also known as fibroid or myoma) is the most common
benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can …

Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that
regulate lipid biosynthesis and adipogenesis by controlling the expression of several …

Mechanosensing describes the ability of a cell to sense mechanical cues of its
microenvironment, including not only all components of force, stress, and strain but also …

Plasma membrane tension regulates many key cellular processes. It is modulated by, and
can modulate, membrane trafficking. However, the cellular pathway (s) involved in this …

The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the
control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo …

Cell migration is an essential process throughout the life of vertebrates, beginning during
embryonic development and continuing throughout adulthood. Stem cells have an inherent …

Communication between cancer cells enables cancer progression and metastasis. While
cell–cell communication in cancer has primarily been examined through chemical …