Programmed cell death in atherosclerosis and vascular calcification

M Li, ZW Wang, LJ Fang, SQ Cheng, X Wang… - Cell death & …, 2022 - nature.com
The concept of cell death has been expanded beyond apoptosis and necrosis to additional
forms, including necroptosis, pyroptosis, autophagy, and ferroptosis. These cell death …

Randall's plaque and calcium oxalate stone formation: role for immunity and inflammation

SR Khan, BK Canales… - Nature Reviews …, 2021 - nature.com
Idiopathic calcium oxalate (CaOx) stones often develop attached to Randall's plaque
present on kidney papillary surfaces. Similar to the plaques formed during vascular …

Vascular calcification—new insights into its mechanism

SJ Lee, IK Lee, JH Jeon - International journal of molecular sciences, 2020 - mdpi.com
Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

AL Durham, MY Speer, M Scatena… - Cardiovascular …, 2018 - academic.oup.com
Vascular calcification is associated with a significant increase in all-cause mortality and
atherosclerotic plaque rupture. Calcification has been determined to be an active process …

Demineralization–remineralization dynamics in teeth and bone

EA Abou Neel, A Aljabo, A Strange… - International journal …, 2016 - Taylor & Francis
Biomineralization is a dynamic, complex, lifelong process by which living organisms control
precipitations of inorganic nanocrystals within organic matrices to form unique hybrid …

Kidney stones

SR Khan, MS Pearle, WG Robertson… - Nature reviews Disease …, 2016 - nature.com
Kidney stones are mineral deposits in the renal calyces and pelvis that are found free or
attached to the renal papillae. They contain crystalline and organic components and are …

Extracellular vesicles in coronary artery disease

CM Boulanger, X Loyer, PE Rautou… - Nature reviews …, 2017 - nature.com
Membrane vesicles released in the extracellular space are composed of a lipid bilayer
enclosing soluble cytosolic material and nuclear components. Extracellular vesicles include …

Role of vascular smooth muscle cell phenotypic switching and calcification in aortic aneurysm formation: involvement of vitamin K-dependent processes

P Petsophonsakul, M Furmanik, R Forsythe… - … , and vascular biology, 2019 - Am Heart Assoc
Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood
vessel degenerates, leading to dilation and eventually vessel wall rupture. Recently, it was …

Cellular crosstalk between endothelial and smooth muscle cells in vascular wall remodeling

N Méndez-Barbero, C Gutiérrez-Muñoz… - International journal of …, 2021 - mdpi.com
Pathological vascular wall remodeling refers to the structural and functional changes of the
vessel wall that occur in response to injury that eventually leads to cardiovascular disease …

Coronary artery calcification: from mechanism to molecular imaging

T Nakahara, MR Dweck, N Narula, D Pisapia… - JACC: Cardiovascular …, 2017 - jacc.org
Vascular calcification is a hallmark of atherosclerosis. The location, density, and confluence
of calcification may change portions of the arterial conduit to a noncompliant structure …