malERA: an updated research agenda for malaria elimination and eradication
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …
overwhelming health, equity, and economic benefits. WHO and countries are setting …
Plasmodium species: master renovators of their host cells
Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …
strategies that they use to survive and thrive within different intracellular environments …
Malaria parasite translocon structure and mechanism of effector export
The putative Plasmodium translocon of exported proteins (PTEX) is essential for transport of
malarial effector proteins across a parasite-encasing vacuolar membrane into host …
malarial effector proteins across a parasite-encasing vacuolar membrane into host …
[HTML][HTML] The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole
DA Gold, AD Kaplan, A Lis, GCL Bett, EE Rosowski… - Cell host & …, 2015 - cell.com
Toxoplasma gondii is a protozoan pathogen in the phylum Apicomplexa that resides within
an intracellular parasitophorous vacuole (PV) that is selectively permeable to small …
an intracellular parasitophorous vacuole (PV) that is selectively permeable to small …
EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX
Intraerythrocytic malaria parasites reside within a parasitophorous vacuolar membrane
(PVM) generated during host cell invasion. Erythrocyte remodelling and parasite metabolism …
(PVM) generated during host cell invasion. Erythrocyte remodelling and parasite metabolism …
A Novel Secreted Protein, MYR1, Is Central to Toxoplasma's Manipulation of Host Cells
The intracellular protozoan Toxoplasma gondii dramatically reprograms the transcriptome of
host cells it infects, including substantially up-regulating the host oncogene c-myc. By …
host cells it infects, including substantially up-regulating the host oncogene c-myc. By …
Clathrin-mediated endocytosis facilitates the internalization of Magnaporthe oryzae effectors into rice cells
E Oliveira-Garcia, TM Tamang, J Park, M Dalby… - The Plant …, 2023 - academic.oup.com
Fungi and oomycetes deliver effectors into living plant cells to suppress defenses and
control plant processes needed for infection. Little is known about the mechanism by which …
control plant processes needed for infection. Little is known about the mechanism by which …
Advances in molecular genetic systems in malaria
Robust tools for analysing gene function in Plasmodium parasites, which are the causative
agents of malaria, are being developed at an accelerating rate. Two decades after genetic …
agents of malaria, are being developed at an accelerating rate. Two decades after genetic …
EXP1 is critical for nutrient uptake across the parasitophorous vacuole membrane of malaria parasites
P Mesén-Ramírez, B Bergmann, TT Tran, M Garten… - PLoS …, 2019 - journals.plos.org
Intracellular malaria parasites grow in a vacuole delimited by the parasitophorous vacuolar
membrane (PVM). This membrane fulfils critical roles for survival of the parasite in its …
membrane (PVM). This membrane fulfils critical roles for survival of the parasite in its …
Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate
Plasmodium falciparum parasites, the causative agents of malaria, modify their host
erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and …
erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and …