m6A in mRNA: an ancient mechanism for fine-tuning gene expression
JY Roignant, M Soller - Trends in Genetics, 2017 - cell.com
Modifications in mRNA constitute ancient mechanisms to regulate gene expression post-
transcriptionally. N 6-methyladenosine (m 6 A) is the most prominent mRNA modification …
transcriptionally. N 6-methyladenosine (m 6 A) is the most prominent mRNA modification …
Multiple functions of m6A RNA methylation in cancer
Y Pan, P Ma, Y Liu, W Li, Y Shu - Journal of hematology & oncology, 2018 - Springer
First identified in 1974, m 6 A RNA methylation, which serves as a predominant internal
modification of RNA in higher eukaryotes, has gained prodigious interest in recent years …
modification of RNA in higher eukaryotes, has gained prodigious interest in recent years …
A unified model for the function of YTHDF proteins in regulating m6A-modified mRNA
S Zaccara, SR Jaffrey - Cell, 2020 - cell.com
Summary N 6-methyladenosine (m 6 A) is the most abundant mRNA nucleotide modification
and regulates critical aspects of cellular physiology and differentiation. m 6 A is thought to …
and regulates critical aspects of cellular physiology and differentiation. m 6 A is thought to …
ALKBH5 regulates anti–PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment
N Li, Y Kang, L Wang, S Huff, R Tang… - Proceedings of the …, 2020 - National Acad Sciences
Although immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment,
many patients do not respond or develop resistance to ICB. N6-methylation of adenosine …
many patients do not respond or develop resistance to ICB. N6-methylation of adenosine …
[HTML][HTML] Programmable m6A modification of cellular RNAs with a Cas13-directed methyltransferase
Abstract N 6-Methyladenosine (m6A) is the most widespread internal messenger RNA
modification in humans. Despite recent progress in understanding the biological roles of …
modification in humans. Despite recent progress in understanding the biological roles of …
The N6-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy
Background: N 6-Methyladenosine (m6A) methylation is the most prevalent internal
posttranscriptional modification on mammalian mRNA. The role of m6A mRNA methylation …
posttranscriptional modification on mammalian mRNA. The role of m6A mRNA methylation …
IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader
The major function of Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is to
regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role …
regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role …
N6-methyladenosine modulates messenger RNA translation efficiency
Summary N 6-methyladenosine (m 6 A) is the most abundant internal modification in
mammalian mRNA. This modification is reversible and non-stoichiometric and adds another …
mammalian mRNA. This modification is reversible and non-stoichiometric and adds another …
ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells
N6-methyladenosine (m6A) represents one of the most common RNA modifications in
eukaryotes. Specific m6A writer, eraser, and reader proteins have been identified. As an …
eukaryotes. Specific m6A writer, eraser, and reader proteins have been identified. As an …
m6A modulates neuronal functions and sex determination in Drosophila
Abstract N 6-methyladenosine RNA (m6A) is a prevalent messenger RNA modification in
vertebrates. Although its functions in the regulation of post-transcriptional gene expression …
vertebrates. Although its functions in the regulation of post-transcriptional gene expression …