Skin diseases such as psoriasis (Ps) and psoriatic arthritis (PsA) are immune-mediated
inflammatory diseases. Overlap of autoinflammatory and autoimmune conditions hinders …

Psoriasis is a prevalent laborious inflammation in skin with alternate phases of remission
and relapses. The current study sought to develop nanostructured lipid carriers (NLCs) …

Diosmin is a flavonoid with promising anti-inflammatory and antioxidant properties.
However, it has difficult physicochemical characteristics since its solubility demands a pH …

Chronic stress is significantly implicated in the worsening of autoimmune disorders,
contributing to elevated inflammation and diminished therapeutic efficacy. Here, in this …

The global incidence of autoimmune diseases is on the rise, and many healthcare
professionals believe that chronic stress plays a prominent role in both the aggravation and …

Background Phosphodiesterase-4 is an enzyme that regulates immune responses and
contributes to the development of psoriasis. Dipyridamole and roflumilast function as …

Psoriasis is an auto-immune condition with high keratinocyte hyperproliferation due to lower
p53 and p22 levels. Tacrolimus, an immune suppressor, is considered one of the most …

The current study was conducted to examine the possible advantages of Heydotis
corymbosa (L.) Lam. extract nanogel as a perspective for enhanced permeation and …

Psoriasis is a chronic inflammatory skin disorder characterized by keratinocyte
hyperproliferation, inflammation, and aberrant differentiation. Imiquimod-induced psoriasis …

Objectives Animal models of skin disease are used to evaluate therapeutics to alleviate
disease. One common clinical dermatological complaint is pruritus (itch), but there is a lack …