Mitochondrial dysfunction in cardiovascular diseases: potential targets for treatment

J Yang, Q Guo, X Feng, Y Liu, Y Zhou - Frontiers in cell and …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are serious public health issues and are responsible for
nearly one-third of global deaths. Mitochondrial dysfunction is accountable for the …

TLR9: a friend or a foe

MM Saber, N Monir, AS Awad, ME Elsherbiny, HF Zaki - Life Sciences, 2022 - Elsevier
The innate immune system is a primary protective line in our body. It confers its protection
through different pattern recognition receptors (PRRs), especially toll like receptors (TLRs) …

The role of endothelial dysfunction in peripheral blood nerve barrier: molecular mechanisms and pathophysiological implications

J Maiuolo, M Gliozzi, V Musolino, C Carresi… - International journal of …, 2019 - mdpi.com
The exchange of solutes between the blood and the nerve tissue is mediated by specific and
high selective barriers in order to ensure the integrity of the different compartments of the …

The pathogenic role of the immune system in erectile dysfunction and Peyronie's disease: focusing on immunopathophysiology and potential therapeutic strategies

VA Giagulli, G Lisco, A De Tullio… - Sexual Medicine …, 2024 - academic.oup.com
Introduction Erectile dysfunction (ED) represents the major cause of male sexual
dysfunction, which is often associated with obesity, diabetes mellitus, atherosclerotic …

Cigarette smoking and erectile dysfunction: an updated review with a focus on pathophysiology, e-cigarettes, and smoking cessation

MS Allen, RC Tostes - Sexual Medicine Reviews, 2023 - academic.oup.com
Introduction Cigarette smoking has major health implications and causes substantial
damage to all organ systems. Approximately one-third of men are active smokers worldwide …

Impact of immune system activation and vascular impairment on male and female sexual dysfunction

FB Calmasini, N Klee, RC Webb… - Sexual medicine …, 2019 - academic.oup.com
Introduction Male and female sexual dysfunction (SD) is considered a multifactorial
condition. Numerous studies have shown the involvement of inflammatory processes in this …

The role of the “anti-inflammatory” couple for the management of hyperuricemia with deposition

A Sansone, Y Reisman, S Meto, S Dolci… - Sexual …, 2022 - academic.oup.com
Introduction Gout is the most prevalent inflammatory crystal arthropathy worldwide and is a
chronic disease requiring strict, lifelong adherence to drug therapy and healthy lifestyles …

Lipids, statins and heart failure: an update

N Katsiki, M Doumas… - Current pharmaceutical …, 2016 - benthamdirect.com
Background: Heart failure (HF) is characterized by cardiac functional and structural
alterations, progressively leading to clinical symptoms and signs. Certain neurohormonal …

Interactions between inflammation and female sexual desire and arousal function

TK Lorenz - Current sexual health reports, 2019 - Springer
Abstract Purpose of Review To describe the current state of research on interactions
between inflammation and female sexual function. Recent Findings Inflammation may …

Causal association of cardiovascular disease with erectile dysfunction: a two‐sample bidirectional Mendelian randomization analysis

M Ye, J Chen, J Ma, J Wang, C Zhang, B Chen… - …, 2023 - Wiley Online Library
Background The association between cardiovascular diseases (CVD), including ischemic
stroke (IS), heart failure (HF), myocardial infarction (MI), and coronary heart disease (CHD) …