Advancing diagnostics and therapy to reach universal cure in childhood ALL
R Pieters, CG Mullighan, SP Hunger - Journal of Clinical Oncology, 2023 - ascopubs.org
Systemic combination chemotherapy and intrathecal chemotherapy markedly increased the
survival rate of children with ALL. In the past two decades, the use of minimal (measurable) …
survival rate of children with ALL. In the past two decades, the use of minimal (measurable) …
Future of treatment of adolescents and young adults with ALL: A vision for collaboration and equity
H Newman, SP Hunger - Journal of Clinical Oncology, 2024 - ascopubs.org
Over the past several decades, survival of children with ALL has improved dramatically with
treatment regimens refined through cooperative group trials. Despite aggressive treatment …
treatment regimens refined through cooperative group trials. Despite aggressive treatment …
Prognostic significance of ETP phenotype and minimal residual disease in T-ALL: a Children's Oncology Group study
The early thymic precursor (ETP) immunophenotype was previously reported to confer poor
outcome in T-cell acute lymphoblastic leukemia (T-ALL). Between 2009 and 2014, 1256 …
outcome in T-cell acute lymphoblastic leukemia (T-ALL). Between 2009 and 2014, 1256 …
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk
S Kimura, CS Park, LE Montefiori, I Iacobucci… - Cancer …, 2024 - aacrjournals.org
Acute lymphoblastic leukemia expressing the gamma delta T-cell receptor (γδ T-ALL) is a
poorly understood disease. We studied 200 children with γδ T-ALL from 13 clinical study …
poorly understood disease. We studied 200 children with γδ T-ALL from 13 clinical study …
[HTML][HTML] Biologic and clinical features of childhood gamma delta T-ALL: identification of STAG2/LMO2 γδ T-ALL as an extremely high risk leukemia in the very young
S Kimura, P Polonen, L Montefiori, CS Park, I Iacobucci… - medRxiv, 2023 - ncbi.nlm.nih.gov
PURPOSE Gamma delta T-cell receptor-positive acute lymphoblastic leukemia (γδ T-ALL) is
a high-risk but poorly characterized disease. METHODS We studied clinical features of 200 …
a high-risk but poorly characterized disease. METHODS We studied clinical features of 200 …
How I treat early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) in children
RJ Summers, DT Teachey, SP Hunger - Blood, 2024 - Elsevier
Early T-precursor acute lymphoblastic leukemia (ETP-ALL) is a unique subtype of immature
T-ALL that was initially associated with a dramatically inferior prognosis as compared to non …
T-ALL that was initially associated with a dramatically inferior prognosis as compared to non …
The Holy Grail of Second Complete Remission in Relapsed Pediatric T-acute Lymphoblastic Leukemia
SK Tasian - The Hematologist, 2024 - ashpublications.org
Clinical outcomes for children and adolescents/young adults (AYAs) with T-acute
lymphoblastic leukemia (T-ALL) and lymphoma (T-LL) have improved markedly in recent …
lymphoblastic leukemia (T-ALL) and lymphoma (T-LL) have improved markedly in recent …
Refined Stratification and Frontline Targeted Therapies Explored in Pediatric T-ALL
J Feldman - 2023 - targetedonc.com
The treatment of pediatric patients with T-cell acute lymphoblastic leukemia (T-ALL) has
benefited from numerous advancements in survival outcomes, but there are pressing needs …
benefited from numerous advancements in survival outcomes, but there are pressing needs …