Intraocular foreign body injuries may result in a wide range of intraocular pathology and
visual outcomes based on the mechanism of injury, type of foreign body, and subsequent …

Inflammation plays a pivotal role in ischemia-induced retinal neovascularization. Targeting
microglia/macrophage-based neuroinflammation presents a promising therapeutic strategy …

Objective The aim of this study was to evaluate the effect of different natural substances on
SIRT1 expression and on AMPK and mTOR phosphorylation. Moreover, we investigated the …

Iron is an important micronutrient for neuronal function and survival. It plays an essential role
in DNA and protein synthesis, neurotransmission and electron transport chain due to its dual …

Ferulic acid (FA), a phenolic compound found in various medicinal plants, has
hepatoprotective effects against oxidative stress and inflammation. Here, we investigated the …

Elevated iron levels are considered to play a role in the neurodegenerative mechanisms that
underlie Alzheimer's and Parkinson's disease. The linkage between hepcidin (Hepc) and …

Inductively coupled plasma mass spectrometry (ICP-MS) was used to quantify the total
amount of trace elements in retina from adult male Sprague-Dawley rats (n= 6) …

Background Iron-overload is one of the risk factors in susceptible individuals. Iron-overload
causes complications such as diastolic dysfunction, arrhythmias, ventricular dilation, and …

The mTOR pathway plays a crucial role in many human diseases, mostly associated with an
over hyperactivity of the mTOR signaling, which makes its inhibitors potentially effective …

Background Retinal ischemia-related eye diseases result in visual dysfunction. This study
investigates the protective effects and mechanisms of Xue-Fu-Zhu-Yu decoction (XFZYD) …