The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

Tumors generate physical forces during growth and progression. These physical forces are
able to compress blood and lymphatic vessels, reducing perfusion rates and creating …

Solid tumors consist of cancer cells and stromal cells, including resident and transiting
immune cells—all ensconced in an extracellular matrix (ECM)—nourished by blood vessels …

The deposition of amyloid-β (Aβ) in the brain is a risk factor for Alzheimer's disease (AD).
Therefore, new strategies for the stimulation of Aβ clearance from the brain can be useful in …

The global number of people with Alzheimer's disease (AD) doubles every 5 years. It has
been established that unless an effective treatment for AD is found, the incidence of AD will …

Abstract Objective Lymphatic vessels (LVs) maintain fluid homeostasis by draining interstitial
fluid. A failure in lymphatic drainage triggers lymphatic diseases such as lymphedema …

Background: The lymph system plays important roles in maintaining fluid balances, the
immune system, and lipid metabolism. After tissue replantation or transfer, some cases suffer …

Myeloid-lymphatic endothelial cell progenitors (M-LECP) are a subset of bone marrow (BM)-
derived cells characterized by expression of M2-type macrophage markers. We previously …

Photodynamic therapy (PDT) is a promising add-on therapy to the current standard of care
for patients with glioblastoma (GBM). The traditional explanation of the anti-cancer PDT …

The lymph nodes (LNs), spleen, and other secondary lymphoid organs (eg, Peyer's patches)
are strategically located in anatomical sites where they collect foreign antigen and antigen …