In survival analysis, time‐varying covariates are covariates whose value can change during
follow‐up. Outcomes in medical research are frequently subject to competing risks (events …

Dementia is a major source of disability worldwide and there are currently no available
disease-modifying treatments. Hearing loss may be associated with increased risk of …

Immune checkpoint inhibitors (ICIs) have yielded remarkable responses but often lead to
immune-related adverse events (irAEs). Although germline causes for irAEs have been …

Background Despite limited and conflicting evidence, hydroxychloroquine, alone or in
combination with azithromycin, is widely used in COVID-19 therapy. Methods We performed …

Objective Population-based data are lacking regarding the risk of overall and cause-specific
mortality across the complete histological spectrum of non-alcoholic fatty liver disease …

Background Findings of retrospective studies suggest that sorafenib maintenance post-
transplantation might reduce relapse in patients with FLT3 internal tandem duplication (FLT3 …

Background Patients who have received mechanical ventilation can have prolonged
cognitive impairment for which there is no known treatment. We aimed to establish whether …

PURPOSE Tisagenlecleucel is a CD19-specific chimeric antigen receptor T-cell therapy, US
Food and Drug Administration–approved for children, adolescents, and young adults …

Importance SARS-CoV-2, which causes COVID-19, poses considerable morbidity and
mortality risks. Studies using data collected during routine clinical practice can supplement …

Background This study examined the incidence of a person's first diagnosis of a selected
chronic disease, and the relationships between modifiable lifestyle risk factors and age to …