Myasthenia gravis: epidemiology, pathophysiology and clinical manifestations
L Dresser, R Wlodarski, K Rezania… - Journal of clinical medicine, 2021 - mdpi.com
Myasthenia gravis (MG) is an autoimmune neurological disorder characterized by defective
transmission at the neuromuscular junction. The incidence of the disease is 4.1 to 30 cases …
transmission at the neuromuscular junction. The incidence of the disease is 4.1 to 30 cases …
Myasthenia gravis: subgroup classification and therapeutic strategies
NE Gilhus, JJ Verschuuren - The Lancet Neurology, 2015 - thelancet.com
Myasthenia gravis is an autoimmune disease that is characterised by muscle weakness and
fatigue, is B-cell mediated, and is associated with antibodies directed against the …
fatigue, is B-cell mediated, and is associated with antibodies directed against the …
Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society
Myasthenia gravis (MG) is an autoimmune antibody-mediated disorder of neuromuscular
synaptic transmission. The clinical hallmark of MG consists of fluctuating fatigability and …
synaptic transmission. The clinical hallmark of MG consists of fluctuating fatigability and …
The different roles of the thymus in the pathogenesis of the various myasthenia gravis subtypes
A Marx, F Pfister, B Schalke, G Saruhan-Direskeneli… - Autoimmunity …, 2013 - Elsevier
The thymus plays distinct roles in the pathogenesis of the different Myasthenia gravis (MG)
subtypes. Inflammatory, neoplastic and age-related alterations of the thymus are of pivotal …
subtypes. Inflammatory, neoplastic and age-related alterations of the thymus are of pivotal …
Epidemiology, diagnostics, and biomarkers of autoimmune neuromuscular junction disorders
AR Punga, P Maddison, JM Heckmann… - The Lancet …, 2022 - thelancet.com
Autoimmune neuromuscular junction disorders are rare. However, myasthenia gravis is
being increasingly recognised in people older than 50 years. In the past 5–10 years …
being increasingly recognised in people older than 50 years. In the past 5–10 years …
Thymus and autoimmunity
A Marx, Y Yamada, K Simon-Keller, B Schalke… - Seminars in …, 2021 - Springer
The thymus prevents autoimmune diseases through mechanisms that operate in the cortex
and medulla, comprising positive and negative selection and the generation of regulatory T …
and medulla, comprising positive and negative selection and the generation of regulatory T …
Autoimmune disorders of the nervous system: pathophysiology, clinical features, and therapy
S Bhagavati - Frontiers in neurology, 2021 - frontiersin.org
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of
several, previously poorly understood, neurological disorders. Autoimmune disorders of the …
several, previously poorly understood, neurological disorders. Autoimmune disorders of the …
Exploring the gut microbiome in myasthenia gravis
The human gut microbiota is vital for maintaining human health in terms of immune system
homeostasis. Perturbations in the composition and function of microbiota have been …
homeostasis. Perturbations in the composition and function of microbiota have been …
Myasthenia gravis and infectious disease
NE Gilhus, F Romi, Y Hong, GO Skeie - Journal of neurology, 2018 - Springer
Background and purpose Myasthenia gravis (MG) is an autoimmune disease with muscular
weakness as the only symptom, and often with immunosuppressive treatment. All these …
weakness as the only symptom, and often with immunosuppressive treatment. All these …
Associations between HLA and autoimmune neurological diseases with autoantibodies
S Muñiz-Castrillo, A Vogrig, J Honnorat - Autoimmunity Highlights, 2020 - Springer
Recently, several autoimmune neurological diseases have been defined by the presence of
autoantibodies against different antigens of the nervous system. These autoantibodies have …
autoantibodies against different antigens of the nervous system. These autoantibodies have …