Highlights•Mutant K13-mediated artemisinin resistance involves reduced hemoglobin
endocytosis.•Artemisinin partial resistance has emerged in Africa.•Novel PfCRT mutations …

The emergence of artemisinin resistance is a major obstacle to the global malaria
eradication/elimination programs. Artemisinin is a very fast-acting antimalarial drug and is …

Background The emergence and spread of multidrug-resistant Plasmodium falciparum in
the Greater Mekong Subregion (GMS) threatens global malaria elimination efforts. Mass …

Background Global interest in malaria elimination has prompted research on active test and
treat (TaT) strategies. Methods A systematic review and meta-analysis were conducted to …

Modern data and computational resources, coupled with algorithmic and theoretical
advances to exploit these, allow disease dynamic models to be parameterised with …

Abstract Background Across the Greater Mekong Subregion, malaria remains a dangerous
infectious disease, particularly for people who visit forested areas where residual …

Cambodia targets malaria elimination by 2025. Rapid elimination will depend on
successfully identifying and clearing malaria foci linked to forests. Expanding and …

Background In the Greater Mekong Sub-region (GMS), malaria elimination efforts are
targeting the asymptomatic parasite reservoirs. Understanding community perceptions about …

Mathematical models are increasingly used to inform decisions throughout product
development pathways from pre-clinical studies to country implementation of novel health …

Background As malaria elimination becomes a goal in malaria-endemic nations, questions
of feasibility become critical. This article explores the potential challenges associated with …