Context Aims of bladder preservation in muscle-invasive bladder cancer (MIBC) are to offer
a quality-of-life advantage and avoid potential morbidity or mortality of radical cystectomy …

Cystectomy is a standard treatment for muscle-invasive bladder cancer (MIBC), but it is life-
altering. We initiated a phase 2 study in which patients with MIBC received four cycles of …

Purpose: This multidisciplinary, evidence-based guideline for clinically non-metastatic
muscle-invasive bladder cancer focuses on the evaluation, treatment and surveillance of …

Bladder cancer is the most common malignancy of the urinary tract and the ninth most
common malignancy in the world, with an estimated overall global 5-year prevalence of …

Identification of potential factors that can stratify a tumor's response to specific therapies will
aid in the selection of cancer therapy. The aim was to highlight the role of programmed cell …

There is uncertainty regarding the use of bladder‐sparing alternatives to standard radical
cystectomy, optimal lymph node dissection techniques, and optimal chemotherapeutic …

Background Standard management of muscle-invasive bladder cancer involves radical
cystectomy with pelvic lymph node dissection. However, patients may be ineligible for …

Purpose: We report the outcomes in patients with muscle invasive bladder cancer from 2
institutions who experienced a clinically complete response to neoadjuvant platinum based …

Background A growing number of investigations have suggested a close link between
cancer stem cells (CSCs), epithelial-to-mesenchymal transition (EMT), and the tumor …

OBJECTIVE: To report long-term outcomes of selective organ preservation for muscle-
invasive bladder cancer (MIBC) using 2 bladder-sparing trimodality approaches …