Glycosylphosphatidylinositol (GPI)-anchored proteins are a specialized class of lipid-
associated neuronal membrane proteins that perform diverse functions in the dynamic …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and cognitive decline. Synaptic impairment is one of the first events to occur in …

We identify biomarkers for disease progression in three type 2 diabetes cohorts
encompassing 2,973 individuals across three molecular classes, metabolites, lipids and …

Traumatic brain injury (TBI) is a critical public health and socioeconomic problem worldwide.
The herb pair Astragali Radix (AR)‐Radix Angelica Sinensis (RAS) is a common prescribed …

Neurodegenerative diseases (NDs) such as Alzheimer's, Parkinson's, Multiple Sclerosis,
Hereditary Spastic Paraplegia, and Amyotrophic Lateral Sclerosis have emerged as the …

Recent studies have shown that Nogo-A and the Nogo-A receptor affect β-amyloid
metabolism and the downstream Rho GTP enzyme signaling pathway, which may affect the …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) that
causes progressive neurological disability in most patients due to neurodegeneration …

Alzheimer's disease is a major neurodegenerative disease characterized by memory loss
and cognitive deficits. Recently, we reported that osmotin, which is a homolog of …

Amyloid Precursor Protein (APP) and its cleavage processes have been widely investigated
in the past, in particular in the context of Alzheimer's Disease (AD). Evidence of an increased …

Metabolic dysfunction is a critical step in the etiopathogenesis of Alzheimer's disease. In this
progressive neurological disorder, impaired zinc homeostasis has a key role that needs to …