Since its initial formalization nearly 20 years ago, the concept of lipid rafts has generated a
tremendous amount of attention and interest and nearly as much controversy. The …

Understanding interactions between nanoparticles (NPs) with biological matter, particularly
cells, is becoming increasingly important due to their growing application in medicine and …

To execute their many vital functions, cell membranes are highly organized. Here, we review
how membrane structure shapes signal transduction across membranes. Recent …

The cytoplasmic side of eukaryotic cell membranes is covered by a dense actin rich cortex.
We present FCS and STED experiments showing that a dense membrane bound actin …

Membrane attack complex/perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins
constitute a major superfamily of pore-forming proteins that act as bacterial virulence factors …

Several groups have recently reported evidence for the emergence of domains in cell
plasma membranes when membrane proteins are organized by ligand binding or assembly …

Killer T cells (cytotoxic T lymphocytes, CTLs) maintain immune homoeostasis by eliminating
virus-infected and cancerous cells. CTLs achieve this by forming an immunological synapse …

This article summarizes a variety of physical mechanisms proposed in the literature, which
can generate micro-and nanodomains in multicomponent lipid bilayers and biomembranes …

The lipid raft hypothesis presents insights into how the cell membrane organizes proteins
and lipids to accomplish its many vital functions. Yet basic questions remain about the …

Images of micrometer-scale domains in lipid bilayers have provided the gold standard of
model-free evidence to understand the domains' shapes, sizes, and distributions …