[HTML][HTML] Superantigen recognition and interactions: functions, mechanisms and applications

AM Deacy, SKE Gan, JP Derrick - Frontiers in Immunology, 2021 - frontiersin.org
Superantigens are unconventional antigens which recognise immune receptors outside
their usual recognition sites eg complementary determining regions (CDRs), to elicit a …

[HTML][HTML] Chronic Rhinosinusitis, S. aureus Biofilm and Secreted Products, Inflammatory Responses, and Disease Severity

G Shaghayegh, C Cooksley, M Ramezanpour… - Biomedicines, 2022 - mdpi.com
Chronic rhinosinusitis (CRS) is a persistent inflammation of the nasal cavity and paranasal
sinuses associated with tissue remodelling, dysfunction of the sinuses' natural defence …

Virulence attributes of successful methicillin-resistant Staphylococcus aureus lineages

JH Jiang, DR Cameron, C Nethercott… - Clinical microbiology …, 2023 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of severe and often
fatal infections. MRSA epidemics have occurred in waves, whereby a previously successful …

[HTML][HTML] The immune evasion roles of Staphylococcus aureus protein A and impact on vaccine development

A Bear, T Locke, S Rowland-Jones… - Frontiers in Cellular …, 2023 - frontiersin.org
While Staphylococcus aureus (S. aureus) bacteria are part of the human commensal flora,
opportunistic invasion following breach of the epithelial layers can lead to a wide array of …

[HTML][HTML] The role of virus infections in Sjögren's syndrome

M Maslinska, K Kostyra-Grabczak - Frontiers in Immunology, 2022 - frontiersin.org
Primary Sjögren's syndrome (pSS) is an autoimmune disease with a clinical picture of not
only mainly exocrine gland involvement, with dryness symptoms, but also internal organ and …

[HTML][HTML] Superantigenic activation of human cardiac mast cells

G Varricchi, S Loffredo, F Borriello, A Pecoraro… - International Journal of …, 2019 - mdpi.com
B cell superantigens, also called immunoglobulin superantigens, bind to the variable
regions of either the heavy or light chain of immunoglobulins mirroring the lymphocyte …

[HTML][HTML] Natural human immunity against staphylococcal protein A relies on effector functions triggered by IgG3

E Boero, AR Cruz, W Pansegrau, C Giovani… - Frontiers in …, 2022 - frontiersin.org
Staphylococcal protein A (SpA) is a multifunctional, highly conserved virulence factor of
Staphylococcus aureus. By binding the Fc portion of all human IgG subclasses apart from …

Antibiotics and antibiotic-resistant bacteria in greywater: Challenges of the current treatment situation and predictions of future scenario

EA Noman, RMSR Mohamed, AA Al-Gheethi… - Environmental …, 2022 - Elsevier
The current work reviews the quantitative microbiological risk assessment of antibiotic-
resistant bacteria (ARB) in greywater and discusses the international strategies currently …

Autoreactivity in naive human fetal B cells is associated with commensal bacteria recognition

JW Chen, TA Rice, JM Bannock, AA Bielecka… - Science, 2020 - science.org
Restricted V (D) J recombination during fetal development was postulated to limit antibody
repertoire breadth and prevent autoimmunity. However, newborn serum contains abundant …

The gut microbiome in systemic lupus erythematosus: lessons from rheumatic fever

GJ Silverman, DF Azzouz, N Gisch… - Nature Reviews …, 2024 - nature.com
For more than a century, certain bacterial infections that can breach the skin and mucosal
barriers have been implicated as common triggers of autoimmune syndromes, especially …