Effectiveness and safety of sofosbuvir/velpatasvir/voxilaprevir as a hepatitis C virus infection salvage therapy in the real world: a systematic review and meta-analysis

J Xie, B Xu, L Wei, C Huang, W Liu - Infectious diseases and therapy, 2022 - Springer
Abstract Introduction Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) is the first direct-
acting antiviral (DAA) therapy approved for patients who have previously failed a DAA …

The role of RASs/RVs in the current management of HCV

K Malandris, G Kalopitas, E Theocharidou… - Viruses, 2021 - mdpi.com
The approval of combination therapies with direct-acting antiviral (DAA) regimens has led to
significant progress in the field of hepatitis C virus (HCV) treatment. Although most patients …

[HTML][HTML] Real-world effectiveness of voxilaprevir/velpatasvir/sofosbuvir in patients following DAA failure

C Graf, R D'Ambrosio, E Degasperi, S Paolucci… - JHEP Reports, 2024 - Elsevier
Background & Aims Voxilaprevir/velpatasvir/sofosbuvir (VOX/VEL/SOF) is highly effective for
re-treatment of direct-acting antiviral (DAA)-experienced patients with chronic HCV infection …

Retreatment for hepatitis C virus direct‐acting antiviral therapy virological failure in primary and tertiary settings: The REACH‐C cohort

JM Carson, B Hajarizadeh, J Hanson… - Journal of viral …, 2022 - Wiley Online Library
Virological failure occurs in a small proportion of people treated for hepatitis C virus (HCV)
with direct‐acting antiviral (DAA) therapies. This study assessed retreatment for virological …

Virological characterization of treatment failures and retreatment outcomes in patients infected with “unusual” HCV genotype 1 subtypes

E Vo-Quang, A Soulier, M Ndebi, C Rodriguez… - Hepatology, 2023 - journals.lww.com
Conclusions: Patients infected with “unusual” HCV genotype 1 subtypes are over-
represented among direct-acting antiviral treatment failures. Most of them were born and …

Implementation of a controlled human infection model for evaluation of HCV vaccine candidates

E Barnes, GS Cooke, GM Lauer, RT Chung - Hepatology, 2023 - journals.lww.com
Hepatitis C virus (HCV) remains a major global health concern. Directly acting antiviral
(DAA) drugs have transformed the treatment of HCV. However, it has become clear that …

Efficacy of ultra-short, response-guided sofosbuvir and daclatasvir therapy for hepatitis C in a single-arm mechanistic pilot study

B Flower, L Mccabe, MA Ansari, C Le Ngoc, TV Thi… - Elife, 2023 - elifesciences.org
Background: World Health Organization has called for research into predictive factors for
selecting persons who could be successfully treated with shorter durations of direct-acting …

Sofosbuvir/velpatasvir/voxilaprevir for hepatitis C virus retreatment in decompensated cirrhosis.

S Patel, MT Martin, SL Flamm - Liver International, 2021 - search.ebscohost.com
Abstract Real world SOF/VEL/VOX retreatment outcomes and viral resistance analysis for
HCV patients with prior failure to DAA therapy. Additionally, all patients either maintained or …

Real‐life effectiveness of sofosbuvir/velpatasvir/voxilaprevir in hepatitis C patients previously treated with sofosbuvir/velpatasvir or glecaprevir/pibrentasvir

JC Ruiz‐Cobo, J Llaneras, X Forns… - Alimentary …, 2024 - Wiley Online Library
Background Sofosbuvir, velpatasvir and voxilaprevir (SOF/VEL/VOX) is the recommended
rescue therapy for patients with chronic hepatitis C infection who fail direct‐acting antivirals …

Effectiveness of pangenotypic retreatment of chronic hepatitis C after prior failure of pangenotypic therapies

J Jaroszewicz, D Zarębska-Michaluk… - Polskie Archiwum …, 2023 - publicum.umed.lodz.pl
Introduction: Despite the overall excellent efficacy of pangenotypic direct-acting antiviral
(DAA) options, there is still a small percentage of patients with hepatitis C virus (HCV) …