Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group
Over the last seven decades, applications using members of the Bacillus subtilis group have
emerged in both food processes and crop protection industries. Their ability to form survival …
emerged in both food processes and crop protection industries. Their ability to form survival …
Actinomycetes: still a source of novel antibiotics
O Genilloud - Natural product reports, 2017 - pubs.rsc.org
Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …
sources for the discovery of new antibiotics with an important number of drugs and analogs …
Antibiotics and bacterial resistance in the 21st century
RJ Fair, Y Tor - Perspectives in medicinal chemistry, 2014 - journals.sagepub.com
Dangerous, antibiotic resistant bacteria have been observed with increasing frequency over
the past several decades. In this review the factors that have been linked to this …
the past several decades. In this review the factors that have been linked to this …
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters
Although biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial
metabolites, our knowledge of their diversity remains limited. Here, we used a novel …
metabolites, our knowledge of their diversity remains limited. Here, we used a novel …
Antibiotics and the gut microbiota
Antibiotics have been a cornerstone of innovation in the fields of public health, agriculture,
and medicine. However, recent studies have shed new light on the collateral damage they …
and medicine. However, recent studies have shed new light on the collateral damage they …
Fungal–fungal co-culture: a primer for generating chemical diversity
SL Knowles, HA Raja, CD Roberts… - Natural Product …, 2022 - pubs.rsc.org
Covering: 2002 to 2020 In their natural environment, fungi must compete for resources. It
has been hypothesized that this competition likely induces the biosynthesis of secondary …
has been hypothesized that this competition likely induces the biosynthesis of secondary …
Antibiotics for emerging pathogens
MA Fischbach, CT Walsh - Science, 2009 - science.org
Antibiotic-resistant strains of pathogenic bacteria are increasingly prevalent in hospitals and
the community. New antibiotics are needed to combat these bacterial pathogens, but …
the community. New antibiotics are needed to combat these bacterial pathogens, but …
Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A
K Yamanaka, KA Reynolds… - Proceedings of the …, 2014 - National Acad Sciences
Recent developments in next-generation sequencing technologies have brought recognition
of microbial genomes as a rich resource for novel natural product discovery. However …
of microbial genomes as a rich resource for novel natural product discovery. However …
Prospects for new antibiotics: a molecule-centered perspective
CT Walsh, TA Wencewicz - The Journal of antibiotics, 2014 - nature.com
There is a continuous need for iterative cycles of antibiotic discovery and development to
deal with the selection of resistant pathogens that emerge as therapeutic application of an …
deal with the selection of resistant pathogens that emerge as therapeutic application of an …
Marine natural products: a new wave of drugs?
R Montaser, H Luesch - Future medicinal chemistry, 2011 - Taylor & Francis
The largely unexplored marine world that presumably harbors the most biodiversity may be
the vastest resource to discover novel 'validated'structures with novel modes of action that …
the vastest resource to discover novel 'validated'structures with novel modes of action that …