This systematic review and meta-analysis examined the associations between obesity and
puberty timing based on scientific evidence. Eight electronic databases were searched up to …

Humans and other species adapt dynamically to changes in daily physical activity,
maintaining total energy expenditure within a narrow range. Chronic exercise thus …

Background Early onset of menarche is one of the most important factors for breast cancer
and other associated health hazards. The aim of this study was to investigate the early age …

Chronic kidney disease (CKD) increasingly affects younger people, including adolescents
and young adults. CKD among females is accompanied by unique reproductive and …

Background Previous studies have examined the association between blood lead levels
and pubertal timing in adolescent girls; however, the evidence is lacking on the role of lead …

Mammographic density refers to the radiological appearance of fibroglandular and adipose
tissue on a mammogram of the breast. Women with relatively high mammographic density …

Aim To systematically appraise and summarise published evidence on the association
between childhood physical activity (PA) and subsequent age at menarche (AAM). Methods …

This is the first of two installments examining early puberty in girls. The first paper will
discuss secular trends in onset of puberty and the possible mechanisms to explain these …

Objectives The purpose of this study was to examine the association of prepubertal body
mass index (BMI) and weight status with pubertal development in boys and girls in …

Background Obesity has been reported to be an important contributing factor for precocious
puberty, especially in girls. The effect of green tea polyphenols on weight reduction in adult …