Overamped: stimulant use and HIV pathogenesis

EJ Ross, RS Williams, M Viamonte, JM Reynolds… - Current HIV/AIDS …, 2023 - Springer
Abstract Purpose of Review In the era of HIV treatment as prevention (TasP), more clarity is
needed regarding whether people with HIV who use stimulants (ie, methamphetamine …

[HTML][HTML] Increased LPS levels coexist with systemic inflammation and result in monocyte activation in severe COVID-19 patients

PC Teixeira, GP Dorneles, PC Santana Filho… - International …, 2021 - Elsevier
Mucosal barrier alterations may play a role in the pathogenesis of several diseases,
including COVID-19. In this study we evaluate the association between bacterial …

Twelve-year neurocognitive decline in HIV is associated with comorbidities, not age: a CHARTER study

RK Heaton, RJ Ellis, B Tang, CM Marra, LH Rubin… - Brain, 2023 - academic.oup.com
Modern antiretroviral therapy (ART) has increased longevity of people with HIV and shifted
the age distribution of the HIV pandemic upward toward that of the general population. This …

Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients

S Chettimada, DR Lorenz, V Misra, SM Wolinsky… - BMC immunology, 2020 - Springer
Abstract Background Extracellular vesicles (EVs) are nano-sized particles secreted by most
cells. EVs carry nucleic acids that hold promise as potential biomarkers in various diseases …

[HTML][HTML] Mini-review: The therapeutic role of cannabinoids in neuroHIV

BJ Yadav-Samudrala, S Fitting - Neuroscience letters, 2021 - Elsevier
In the era of combined antiretroviral therapy (cART), human immunodeficiency virus type 1
(HIV-1) is considered a chronic disease with an inflammatory component that specifically …

Endotoxin tolerance and low activation of TLR-4/NF-κB axis in monocytes of COVID-19 patients

GP Dorneles, PC Teixeira, A Peres… - Journal of Molecular …, 2023 - Springer
Higher endotoxin in the circulation may indicate a compromised state of host immune
response against coinfections in severe COVID-19 patients. We evaluated the inflammatory …

Impact of cannabis use on immune cell populations and the viral reservoir in people with HIV on suppressive antiretroviral therapy

SD Falcinelli, AD Cooper-Volkheimer… - The Journal of …, 2023 - academic.oup.com
Background Human immunodeficiency virus (HIV) infection remains incurable due to the
persistence of a viral reservoir despite antiretroviral therapy (ART). Cannabis (CB) use is …

Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana

L Yin, AR Dinasarapu, SA Borkar, KF Chang… - Retrovirology, 2022 - Springer
Background Marijuana's putative anti-inflammatory properties may benefit HIV-associated
comorbidities. How recreational marijuana use affects gene expression in peripheral blood …

Cocaine use associated gut permeability and microbial translocation in people living with HIV in the Miami Adult Study on HIV (MASH) cohort

J Hernandez, JA Tamargo, S Sales Martinez… - PloS one, 2022 - journals.plos.org
Objective Determine if cocaine use impacts gut permeability, promotes microbial
translocation and immune activation in people living with HIV (PLWH) using effective …

Short-term increase in risk of overweight and concomitant systolic blood pressure elevation in treatment-naïve persons starting INSTI-based antiretroviral therapy

R Galdamez, JA García, M Fernández… - Open forum …, 2019 - academic.oup.com
Objective Integrase strand transfer inhibitors (INSTI) have been associated with weight gain,
but their effect on short-term overweight and obesity incidence, blood pressure (BP), and …