One of the grand challenges of biophysical chemistry is to understand the principles that
govern protein misfolding and aggregation, which is a highly complex process that is …

Elucidating the details of the formation, stability, interactions, and reactivity of biomolecular
systems under extreme environmental conditions, including high salt concentrations in …

Rhamnolipids represent a large class of biologically produced surface-active compounds,
which participate in various essential cellular functions. While many studies have reported …

Ras proteins are proto-oncogenes that function as molecular switches linking extracellular
stimuli with an overlapping but distinctive range of biological outcomes. Although …

Several proteins and peptides are known to form cytotoxic oligomers and amyloid fibrils—
mainly consisting of intermolecular cross-β-sheets—upon misfolding and self-association.[1] …

Lipid nanodiscs are macromolecular assemblies, where a scaffold protein is wrapped
around a nanosized disc of a lipid bilayer, thus protecting the hydrocarbon chains at the disc …

There are several proteins, which can cause allergic reaction if they are inhaled or ingested.
Our everyday food can also contain such proteins. Food allergy is an IgE-mediated immune …

Fibrillar aggregates of the islet amyloid polypeptide (IAPP) and amyloid-β (Aβ) are known to
deposit at pancreatic β-cells and neuronal cells and are associated with the cell …

K-Ras4B is a membrane-bound small GTPase with a prominent role in cancer development.
It contains a polybasic farnesylated C-terminus that is required for the correct localization …

The sterilizing effect of a combination of heat (80, 90, and 100° C) and ε-polylysine (ε-PL,
0.25 and 1 g/L) treatments on Bacillus subtilis spores was investigated and compared with …