Mammalian target of rapamycin (mTOR) serves an important role in regulating various
biological processes, including cell proliferation, metabolism, apoptosis and autophagy …

Cancer cells largely rely on aerobic glycolysis or the Warburg effect to generate essential
biomolecules and energy for their rapid growth. The key modulators in glycolysis including …

Purpose: This study aimed to identify the potential prognostic role of HK3 and provide clues
about glycolysis and the microenvironmental characteristics of ccRCC. Methods: Based on …

Metabolic rearrangement is a marker of cancer that has been widely studied in recent years.
One of the major metabolic characteristics of tumor cells is the high levels of glycolysis, even …

Multiple myeloma (MM) is an incurable hematopoietic neoplasm derived from plasma cells,
and existing in the bone marrow. Recent developments in the field of myeloma onco‐biology …

Targeted therapies of melanoma are of urgent need considering the resistance of this
aggressive type of cancer to chemotherapeutics. The voltage-dependent anion channel 1 …

Abstract Background Numerous circular RNAs (circRNAs) have been recognized as vital
modulators of human malignancies, including glioma. Whereas, the functional role of …

Background Colorectal cancer (CRC) is a common cancer worldwide. The main cause of
death in CRC includes tumor progression and metastasis. At molecular level, these …

Aberrant expression of miRNAs contributes to the development of human malignancies. A
recent study revealed that miR-142-5p is increased in the serum of colorectal cancer (CRC) …

Malignant melanoma exhibits a distinct metabolic phenotype with high glycolytic activity.
Previously, we have shown that glucose transporter isoform 1 (GLUT1) favors growth and …