Study objectives To provide a systematic overview of the literature investigating patient and
tumor factors that are predictive of survival for patients with non-small cell lung cancer …

Differential diagnosis of suspicious lung masses is essential for the selection of the
appropriate therapy strategy. While non-small cell lung cancer (NSCLC) in early stages and …

Background: The analysis of plasma cell-free DNA (cfDNA) is expected to provide useful
biomarkers for early diagnosis of non-small-cell lung cancer (NSCLC). However, it remains …

Patients with cancer who have high serum levels of squamous cell carcinoma antigen 1
(SCCA1, now referred to as SERPINB3) commonly experience treatment resistance and …

Cathepsins have long been considered as housekeeping molecules. However, specific
functions have also been attributed to each one of these lysosomal proteases. Squamous …

Detection of lung cancer at an early stage is necessary for successful therapy and improved
survival rates. We performed a bottom-up proteomics analysis using a two-dimensional LC …

Mounting evidence indicates that oncogenic Ras can modulate cell autonomous
inflammatory cytokine production, although the underlying mechanism remains unclear …

We recruited 805 patients with suspicious pulmonary masses that were identified finally as
lung cancer or benign pulmonary masses. The serum levels of four tumor markers, including …

High preoperative serum midkine concentration is associated with poor survival in patients
with esophageal cancer, even after radical surgery, and thus may have prognostic value …

OBJECTIVE: Quantitative analysis of circulating cell free DNA is considered as a possible
aid for lung cancer screening. We aimed to comprehensively review the evidence for use of …