Paracetamol use during pregnancy—a call for precautionary action

AZ Bauer, SH Swan, D Kriebel, Z Liew… - Nature Reviews …, 2021 - nature.com
Abstract Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …

Long‐term adverse effects of paracetamol–a review

JC McCrae, EE Morrison, IM MacIntyre… - British journal of …, 2018 - Wiley Online Library
Paracetamol (acetaminophen) is the most commonly used drug in the world, with a long
record of use in acute and chronic pain. In recent years, the benefits of paracetamol use in …

Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders

TC Theoharides, I Tsilioni, AB Patel, R Doyle - Translational psychiatry, 2016 - nature.com
Autism spectrum disorders (ASDs) affect as many as 1 in 45 children and are characterized
by deficits in sociability and communication, as well as stereotypic movements. Many …

Prenatal fever and autism risk

M Hornig, MA Bresnahan, X Che, AF Schultz… - Molecular …, 2018 - nature.com
Some studies suggest that prenatal infection increases risk of autism spectrum disorders
(ASDs). This study was undertaken in a prospective cohort in Norway to examine whether …

[HTML][HTML] Prenatal and postnatal exposure to acetaminophen in relation to autism spectrum and attention-deficit and hyperactivity symptoms in childhood: Meta-analysis …

S Alemany, C Avella-García, Z Liew… - European journal of …, 2021 - Springer
The potential etiological role of early acetaminophen exposure on Autism Spectrum
Conditions (ASC) and Attention-Deficit/Hyperactivity Disorder (ADHD) is inconclusive. We …

Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition

V Warrier, KL Grasby, F Uzefovsky, R Toro… - Molecular …, 2018 - nature.com
We conducted a genome-wide meta-analysis of cognitive empathy using the 'Reading the
Mind in the Eyes' Test (Eyes Test) in 88,056 research volunteers of European Ancestry …

Maternal immune activation as an epidemiological risk factor for neurodevelopmental disorders: Considerations of timing, severity, individual differences, and sex in …

MB Hall, DE Willis, EL Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence suggests that one's risk of being diagnosed with a
neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …

Association of cord plasma biomarkers of in utero acetaminophen exposure with risk of attention-deficit/hyperactivity disorder and autism spectrum disorder in …

Y Ji, RE Azuine, Y Zhang, W Hou, X Hong… - JAMA …, 2020 - jamanetwork.com
Importance Prior studies have raised concern about maternal acetaminophen use during
pregnancy and increased risk of attention-deficit/hyperactivity disorder (ADHD) and autism …

Prenatal exposure to acetaminophen and risk for attention deficit hyperactivity disorder and autistic spectrum disorder: a systematic review, meta-analysis, and meta …

R Masarwa, H Levine, E Gorelik, S Reif… - American journal of …, 2018 - academic.oup.com
Acetaminophen is the analgesic and antipyretic most commonly used during pregnancy.
Evidence of neurodisruptive properties is accumulating. Therefore, we sought to evaluate …

Prenatal paracetamol exposure and child neurodevelopment: A review

AZ Bauer, D Kriebel, MR Herbert, CG Bornehag… - Hormones and …, 2018 - Elsevier
Background The non-prescription medication paracetamol (acetaminophen, APAP) is
currently recommended as a safe pain and fever treatment during pregnancy. However …