Cystic fibrosis: a mucosal immunodeficiency syndrome
TS Cohen, A Prince - Nature medicine, 2012 - nature.com
Cystic fibrosis transmembrane conductance regulator (CFTR) functions as a channel that
regulates the transport of ions and the movement of water across the epithelial barrier …
regulates the transport of ions and the movement of water across the epithelial barrier …
Vibrio vulnificus: An Environmental and Clinical Burden
SP Heng, V Letchumanan, CY Deng… - Frontiers in …, 2017 - frontiersin.org
Vibrio vulnificus is a Gram negative, rod shaped bacterium that belongs to the family
Vibrionaceae. It is a deadly, opportunistic human pathogen which is responsible for the …
Vibrionaceae. It is a deadly, opportunistic human pathogen which is responsible for the …
Pseudomonas aeruginosa elastase (LasB) as a therapeutic target
MJ Everett, DT Davies - Drug Discovery Today, 2021 - Elsevier
The Pseudomonas aeruginosa LasB elastase (elastase B, pseudolysin) is the predominant
protease in the P. aeruginosa secretome. It has been shown to hydrolyse a vast array of host …
protease in the P. aeruginosa secretome. It has been shown to hydrolyse a vast array of host …
Virulence Characteristics and an Action Mode of Antibiotic Resistance in Multidrug-Resistant Pseudomonas aeruginosa
Pseudomonas aeruginosa displays intrinsic resistance to many antibiotics and known to
acquire actively genetic mutations for further resistance. In this study, we attempted to …
acquire actively genetic mutations for further resistance. In this study, we attempted to …
Microevolution of Pseudomonas aeruginosa to a Chronic Pathogen of the Cystic Fibrosis Lung
M Hogardt, J Heesemann - Between pathogenicity and commensalism, 2012 - Springer
Pseudomonas aeruginosa is the leading pathogen of chronic cystic fibrosis (CF) lung
infection. Life-long persistance of P. aeruginosa in the CF lung requires a sophisticated …
infection. Life-long persistance of P. aeruginosa in the CF lung requires a sophisticated …
Anti-PqsR compounds as next-generation antibacterial agents against Pseudomonas aeruginosa: A review
Nowadays, due to spreading antibiotic resistance among clinically relevant pathogens, the
requirement of novel therapeutic approaches is felt more than ever. One of the alternative …
requirement of novel therapeutic approaches is felt more than ever. One of the alternative …
Anaerobiosis influences virulence properties of Pseudomonas aeruginosa cystic fibrosis isolates and the interaction with Staphylococcus aureus
The airways of individuals with cystic fibrosis (CF) are abundantly colonised by
Staphylococcus aureus and Pseudomonas aeruginosa. Co-infecting hypoxic regions of …
Staphylococcus aureus and Pseudomonas aeruginosa. Co-infecting hypoxic regions of …
The role of Vibrio vulnificus virulence factors and regulators in its infection-induced sepsis
G Li, MY Wang - Folia microbiologica, 2020 - Springer
Due to the development of Marine aquaculture, infections caused by Vibrio vulnificus are
common all over the world. Symptoms of V. vulnificus infection vary from gastrointestinal …
common all over the world. Symptoms of V. vulnificus infection vary from gastrointestinal …
1H NMR-Based Global Metabolic Studies of Pseudomonas aeruginosa upon Exposure of the Quorum Sensing Inhibitor Resveratrol
Quorum sensing (QS) is a process of bacterial communication that has been a novel target
for drug discovery. Pyocyanin quantification assay confirmed that resveratrol was an …
for drug discovery. Pyocyanin quantification assay confirmed that resveratrol was an …
Protective role of gut commensal microbes against intestinal infections
The human gastrointestinal tract is colonized by multitudes of microorganisms that exert
beneficial effects on human health. Mounting evidence suggests that intestinal microbiota …
beneficial effects on human health. Mounting evidence suggests that intestinal microbiota …