New Findings What is the topic of this review? This is the first review to look across the broad
field of 'cold water immersion'and to determine the threats and benefits associated with it as …

The effects of type 1 and type 2 diabetes on the body's physiological response to thermal
stress is a relatively new topic in research. Diabetes tends to place individuals at greater risk …

Indirect evidence from human studies suggests that brown adipose tissue (BAT)
thermogenesis is fueled predominantly by fatty acids hydrolyzed from intracellular …

Spontaneous glucose uptake by brown adipose tissue (BAT) is lower in overweight or obese
individuals and in diabetes. However, BAT metabolism has not been previously investigated …

As endotherms, humans exposed to a compensable cold environment rely on an increase in
thermogenic rate to counteract heat lost to the environment, thereby maintaining a stable …

Cold weather can have deleterious effects on health, tolerance, and performance. This
paper will review the physiological responses and external factors that impact cold tolerance …

Humans have inherited complex neural circuits which drive behavioral, somatic, and
autonomic thermoregulatory responses to defend their body temperature. While they are …

Daily compensable cold exposure in humans reduces shivering by~ 20% without changing
total heat production, partly by increasing brown adipose tissue thermogenic capacity and …

Habituation is an adaptation seen in many organisms, defined by a reduction in the
response to repeated stimuli. Evolutionarily, habituation is thought to benefit the organism by …

During maximal cold challenge (cold-induced V̇ O2, max) in hypoxia, highland deer mice
(Peromyscus maniculatus) show higher rates of circulatory fatty acid delivery compared with …