Simple Summary Copper is an essential element for human life. However, its redox activity
can be detrimental for the cell that developed highly coordinated pathways to chelate and …

Acute pancreatitis, chronic pancreatitis and pancreatic cancer are responsible for most of the
burden of exocrine pancreatic disease. Glandular damage from recurrent bouts of acute …

The past two decades have witnessed an explosion in our understanding of pancreatic
cancer, and it is now clear that pancreatic cancer is a disease of inherited (germ-line) and …

Background: The precise details of pancreatic ductal adenocarcinoma (PDAC)
pathogenesis are still insufficiently known, requiring the use of higthroughput methods …

The liver and pancreas arise from a common multipotent population of endoderm cells and
share many aspects of their early development. Yet each tissue originates from multiple …

Oncoproteomics is the study of proteins and their interactions in a cancer cell by proteomic
technologies. Proteomic research first came to the fore with the introduction of two …

Background The complexity and heterogeneity of the human plasma proteome have
presented significant challenges in the identification of protein changes associated with …

Cancer is one of the deadliest diseases in the world causing record number of mortalities in
both developed and undeveloped countries. Despite a lot of advances and breakthroughs in …

Since antiquity, humans have used body fluids like saliva, urine and sweat for the diagnosis
of diseases. The amount, color and smell of body fluids are still used in many traditional …

Background and aims: Pancreatic cancer is among the most dismal of human malignancies.
Current therapeutic strategies are virtually ineffective in controlling advanced, metastatic …