Regulation of postabsorptive and postprandial glucose metabolism by insulin-dependent and insulin-independent mechanisms: an integrative approach
GD Dimitriadis, E Maratou, A Kountouri, M Board… - Nutrients, 2021 - mdpi.com
Glucose levels in blood must be constantly maintained within a tight physiological range to
sustain anabolism. Insulin regulates glucose homeostasis via its effects on glucose …
sustain anabolism. Insulin regulates glucose homeostasis via its effects on glucose …
Regulation of adipocyte lipolysis
G Frühbeck, L Méndez-Giménez… - Nutrition research …, 2014 - cambridge.org
In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …
Ghrelin suppresses glucose-stimulated insulin secretion and deteriorates glucose tolerance in healthy humans
J Tong, RL Prigeon, HW Davis, M Bidlingmaier… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE The orexigenic gut hormone ghrelin and its receptor are present in pancreatic
islets. Although ghrelin reduces insulin secretion in rodents, its effect on insulin secretion in …
islets. Although ghrelin reduces insulin secretion in rodents, its effect on insulin secretion in …
The molecular brakes of adipose tissue lipolysis
Y Li, Z Li, DA Ngandiri, M Llerins Perez, A Wolf… - Frontiers in …, 2022 - frontiersin.org
Adaptation to changes in energy availability is pivotal for the survival of animals. Adipose
tissue, the body's largest reservoir of energy and a major source of metabolic fuel, exerts a …
tissue, the body's largest reservoir of energy and a major source of metabolic fuel, exerts a …
Gut-derived serotonin is a multifunctional determinant to fasting adaptation
Energy release from cellular storage is mandatory for survival during fasting. This is
achieved through lipolysis and liver gluconeogenesis. We show here that in the mouse, gut …
achieved through lipolysis and liver gluconeogenesis. We show here that in the mouse, gut …
Physiological effect of ghrelin on body systems
Ghrelin is a relatively novel multifaceted hormone that has been found to exert a plethora of
physiological effects. In this review, we found/confirmed that ghrelin has effect on all body …
physiological effects. In this review, we found/confirmed that ghrelin has effect on all body …
The importance of caloric restriction in the early improvements in insulin sensitivity after Roux-en-Y gastric bypass surgery
JM Isbell, RA Tamboli, EN Hansen, J Saliba… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE Many of the metabolic benefits of Roux-en-Y gastric bypass (RYGB) occur
before weight loss. In this study we investigated the influence of caloric restriction on the …
before weight loss. In this study we investigated the influence of caloric restriction on the …
Ghrelin's relationship to blood glucose
Much effort has been directed at studying the orexigenic actions of administered ghrelin and
the potential effects of the endogenous ghrelin system on food intake, food reward, body …
the potential effects of the endogenous ghrelin system on food intake, food reward, body …
[HTML][HTML] Impact of different bariatric surgical procedures on insulin action and β-cell function in type 2 diabetes
E Ferrannini, G Mingrone - Diabetes care, 2009 - ncbi.nlm.nih.gov
The prevalence of obesity appears to have reached a plateau in the US between 2003 and
2007 (1), but the obesity epidemic is still rampant in many other countries—especially in the …
2007 (1), but the obesity epidemic is still rampant in many other countries—especially in the …
[HTML][HTML] Intestinal cholecystokinin controls glucose production through a neuronal network
GWC Cheung, A Kokorovic, CKL Lam, M Chari… - Cell metabolism, 2009 - cell.com
Cholecystokinin (CCK) is a peptide hormone that is released from the gut in response to
nutrients such as lipids to lower food intake. Here we report that a primary increase of CCK …
nutrients such as lipids to lower food intake. Here we report that a primary increase of CCK …