Natural products and phytochemicals as potential anti‐SARS‐CoV‐2 drugs
The current pandemic responsible for the crippling of the health care system is caused by
the novel SARS‐CoV‐2 in 2019 and leading to coronavirus disease 2019 (COVID‐19). The …
the novel SARS‐CoV‐2 in 2019 and leading to coronavirus disease 2019 (COVID‐19). The …
Structures of the SARS-CoV-2 spike glycoprotein and applications for novel drug development
XH Liu, T Cheng, BY Liu, J Chi, T Shu… - Frontiers in …, 2022 - frontiersin.org
COVID-19 caused by SARS-CoV-2 has raised a health crisis worldwide. The high morbidity
and mortality associated with COVID-19 and the lack of effective drugs or vaccines for SARS …
and mortality associated with COVID-19 and the lack of effective drugs or vaccines for SARS …
Synthesis, characterization, and inhibition study of novel substituted phenylureido sulfaguanidine derivatives as α‐glycosidase and cholinesterase inhibitors
A series of six N‐carbamimidoyl‐4‐(3‐substituted phenylureido) benzenesulfonamide
derivatives were synthesized by reaction of sulfaguanidine with aromatic isocyanates. In …
derivatives were synthesized by reaction of sulfaguanidine with aromatic isocyanates. In …
Critical role of nitric oxide in impeding COVID-19 transmission and prevention: a promising possibility
R Rajendran, A Chathambath, AG Al-Sehemi… - … Science and Pollution …, 2022 - Springer
COVID-19 is a serious respiratory infection caused by a beta-coronavirus that is closely
linked to SARS. Hypoxemia is a symptom of infection, which is accompanied by acute …
linked to SARS. Hypoxemia is a symptom of infection, which is accompanied by acute …
Novel Drug Design for Treatment of COVID‐19: A Systematic Review of Preclinical Studies
Background. Since the beginning of the novel coronavirus (SARS‐CoV‐2) disease
outbreak, there has been an increasing interest in discovering potential therapeutic agents …
outbreak, there has been an increasing interest in discovering potential therapeutic agents …
Plant-derived compounds effectively inhibit the main protease of SARS-CoV-2: An in silico approach
The current coronavirus disease 2019 (COVID-19) pandemic, caused by the coronavirus 2
(SARS-CoV-2), involves severe acute respiratory syndrome and poses unprecedented …
(SARS-CoV-2), involves severe acute respiratory syndrome and poses unprecedented …
Development of a novel class of pyridazinone derivatives as selective MAO-B inhibitors
Sixteen compounds (TR1–TR16) were synthesized and evaluated for their inhibitory
activities against monoamine oxidase A and B (MAOs). Most of the derivatives showed …
activities against monoamine oxidase A and B (MAOs). Most of the derivatives showed …
Virtual screening and in vitro validation of natural compound inhibitors against SARS-CoV-2 spike protein
The COVID-19 pandemic caused by the SARS-CoV-2 virus has led to a major public health
burden and has resulted in millions of deaths worldwide. As effective treatments are limited …
burden and has resulted in millions of deaths worldwide. As effective treatments are limited …
Treating COVID-19 with Medicinal Plants: Is It Even Conceivable? A Comprehensive Review
H Al-Jamal, S Idriss, R Roufayel, Z Abi Khattar… - Viruses, 2024 - mdpi.com
In 2020, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) challenged the
world with a global outbreak that led to millions of deaths worldwide. Coronavirus disease …
world with a global outbreak that led to millions of deaths worldwide. Coronavirus disease …
Exploring the potential of chemical inhibitors for targeting post-translational glycosylation of coronavirus (SARS-CoV-2)
The Spike (S) protein of SARS-CoV-2 expressed on the viral cell surface is of particular
importance as it facilitates viral entry into the host cells. The S protein is heavily glycosylated …
importance as it facilitates viral entry into the host cells. The S protein is heavily glycosylated …