Placebo and Nocebo Effects Placebo and nocebo effects (effects of patients' positive and
negative expectations) are powerful and pervasive in clinical practice. Neurobiologic …

Despite their ubiquitous presence, placebos and placebo effects retain an ambiguous and
unsettling presence in biomedicine. Specifically focused on chronic pain, this review …

The concept of alliance reflects the collaborative relationship between a clinician and a
patient, defined as consisting of three elements: a) the agreement on the goals of treatment; …

Objective To evaluate the efficacy and safety of eptinezumab, a humanized anti-calcitonin
gene-related peptide monoclonal antibody, in the preventive treatment of episodic migraine …

Objective To evaluate the efficacy and safety of eptinezumab, a humanized anti–calcitonin
gene-related peptide monoclonal antibody, in the preventive treatment of chronic migraine …

Placebo effects are beneficial effects that are attributable to the brain–mind responses to the
context in which a treatment is delivered rather than to the specific actions of the drug. They …

Open-label placebos (OLPs) are placebos without deception in the sense that patients know
that they are receiving a placebo. The objective of our study is to systematically review and …

Placebo effects are often considered the effects of an “inert substance,” but that
characterization is misleading. In a broad sense, placebo effects are improvements in …

The content and organization of mental health care have been heavily influenced by the
view that mental difficulties come as diagnosable disorders that can be treated by specialist …

Pharmacological strategies for pain management have primarily focused on dampening
ascending neurotransmission and on opioid receptor–mediated therapies. Little is known …