An elegant mind: learning and memory in Caenorhabditis elegans

EL Ardiel, CH Rankin - Learning & memory, 2010 - learnmem.cshlp.org
This article reviews the literature on learning and memory in the soil-dwelling nematode
Caenorhabditis elegans. Paradigms include nonassociative learning, associative learning …

Diacylglycerol kinases: at the hub of cell signalling

I Mérida, A Avila-Flores, E Merino - Biochemical Journal, 2008 - portlandpress.com
DGKs (diacylglycerol kinases) are members of a unique and conserved family of
intracellular lipid kinases that phosphorylate DAG (diacylglycerol), catalysing its conversion …

The neural circuits and synaptic mechanisms underlying motor initiation in C. elegans

BJ Piggott, J Liu, Z Feng, SA Wescott, XZS Xu - Cell, 2011 - cell.com
C. elegans is widely used to dissect how neural circuits and genes generate behavior.
During locomotion, worms initiate backward movement to change locomotion direction …

How Caenorhabditis elegans Senses Mechanical Stress, Temperature, and Other Physical Stimuli

MB Goodman, P Sengupta - Genetics, 2019 - academic.oup.com
Caenorhabditis elegans lives in a complex habitat in which they routinely experience large
fluctuations in temperature, and encounter physical obstacles that vary in size and …

A high-resolution morphological and ultrastructural map of anterior sensory cilia and glia in Caenorhabditis elegans

DB Doroquez, C Berciu, JR Anderson, P Sengupta… - Elife, 2014 - elifesciences.org
Many primary sensory cilia exhibit unique architectures that are critical for transduction of
specific sensory stimuli. Although basic ciliogenic mechanisms are well described, how …

Running hot and cold: behavioral strategies, neural circuits, and the molecular machinery for thermotaxis in C. elegans and Drosophila

PA Garrity, MB Goodman, AD Samuel… - Genes & …, 2010 - genesdev.cshlp.org
Like other ectotherms, the roundworm Caenorhabditis elegans and the fruit fly Drosophila
melanogaster rely on behavioral strategies to stabilize their body temperature. Both animals …

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9

S Yang, D Park, L Manning, SE Hill, M Cao, Z Xuan… - Neuron, 2022 - cell.com
Autophagy is a cellular degradation pathway essential for neuronal health and function.
Autophagosome biogenesis occurs at synapses, is locally regulated, and increases in …

Degeneracy and neuromodulation among thermosensory neurons contribute to robust thermosensory behaviors in Caenorhabditis elegans

M Beverly, S Anbil, P Sengupta - Journal of Neuroscience, 2011 - Soc Neuroscience
Animals must ensure that they can execute behaviors important for physiological
homeostasis under constantly changing environmental conditions. The neural mechanisms …

Functional organization of a neural network for aversive olfactory learning in Caenorhabditis elegans

H Ha, M Hendricks, Y Shen, CV Gabel, C Fang-Yen… - Neuron, 2010 - cell.com
Many animals use their olfactory systems to learn to avoid dangers, but how neural circuits
encode naive and learned olfactory preferences, and switch between those preferences, is …

Bidirectional temperature-sensing by a single thermosensory neuron in C. elegans

D Ramot, BL MacInnis, MB Goodman - Nature neuroscience, 2008 - nature.com
Humans and other animals can sense temperature changes as small as 0.1° C. How
animals achieve such exquisite sensitivity is poorly understood. By recording from the C …