Recent advances in molecular studies on cochlear development and regeneration

Y Sun, Z Liu - Current Opinion in Neurobiology, 2023 - Elsevier
The auditory organ cochlea harbors two types of sound receptors, inner hair cells (IHCs) and
outer hair cells (OHCs), which are innervated by spiral (auditory) ganglion neurons (SGNs) …

Stem cells as potential therapeutics for hearing loss

Q Fang, Y Wei, Y Zhang, W Cao, L Yan… - Frontiers in …, 2023 - frontiersin.org
Hearing impairment is a global health problem. Stem cell therapy has become a cutting-
edge approach to tissue regeneration. In this review, the recent advances in stem cell …

GelMA/PEDOT: PSS Composite Conductive Hydrogel-Based Generation and Protection of Cochlear Hair Cells through Multiple Signaling Pathways

F Tan, X Li, X Li, M Xu, KA Shahzad, L Hou - Biomolecules, 2024 - mdpi.com
Recent advances in cochlear implantology are exemplified by novel functional strategies
such as bimodal electroacoustic stimulation, in which the patient has intact low-frequency …

Ptch1 is essential for cochlear marginal cell differentiation and stria vascularis formation

T Qin, KKH So, CC Hui, MH Sham - Cell Reports, 2024 - cell.com
A common cause of deafness in humans is dysregulation of the endocochlear potential
generated by the stria vascularis (SV). Thus, proper formation of the SV is critical for hearing …

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis

S Yu, Y Lin, Y Yang, X Jin, B Liao, D Lu, J Huang - Human Genomics, 2024 - Springer
Background Epidemiological studies have revealed a significant association between
impaired kidney function and certain mental disorders, particularly bipolar disorder (BIP) and …

SOX2-Sensing: Insights into the Role of SOX2 in the Generation of Sensory Cell Types in Vertebrates

S Mercurio - International Journal of Molecular Sciences, 2023 - mdpi.com
The SOX2 transcription factor is a key regulator of nervous system development, and its
mutation in humans leads to a rare disease characterized by severe eye defects, cognitive …