The discovery of electric fields in biological tissues has led to efforts in developing
technologies utilizing electrical stimulation for therapeutic applications. Native tissues, such …

Osteoarthritis (OA) affects millions of people and results in weakened hyaline cartilage due
to overloading. During joint articulation, hyaline cartilage must withstand high loads while …

The strain-generated potential (SGP) is a well-established mechanism in cartilaginous
tissues whereby mechanical forces generate electrical potentials. In articular cartilage (AC) …

Laboratory experiments are performed to understand the controlling parameters of the
electrical field associated with the seepage of water through a porous material. We use …

Mechanical loading on articular cartilage can induce many physical and chemical stimuli on
chondrocytes residing in the extracellular matrix (ECM). Intracellular calcium ([Ca2+] i) …

The unknown and variable speed of sound may impair accuracy of the acoustic
measurement of cartilage properties. In this study, relationships between the speed of sound …

In vitro electromechanical and biomechanical testing of articular cartilage provide critical
information about the structure and function of this tissue. Difficulties obtaining fresh tissue …

Recent advances in the development of new drugs to halt or even reverse the progression of
Osteoarthritis at an early‐stage requires new tools to detect early degeneration of articular …

Objective: We have previously developed a handheld ultrasound indentation instrument for
the diagnosis of cartilage degeneration. The instrument has been demonstrated to be …

Summary Objective The hand-held Arthro-BST™ device is used to map electromechanical
properties of articular cartilage. The purpose of the study was to evaluate correlation of …