The biconcave shape and corresponding deformability of the human red blood cell (RBC) is
an essential feature of its biological function. This feature of RBCs can be critically affected …

Clinical manifestations of Plasmodium falciparum infection are induced by the asexual
stages of the parasite that develop inside red blood cells (RBCs). Because splenic …

Malaria and the Spleen In this report, patients living in a malaria-endemic area underwent
trauma-related splenectomy. In these asymptomatic patients who were naturally infected …

Red blood cells (RBCs) can be cleared from circulation when alterations in their size, shape,
and deformability are detected. This function is modulated by the spleen-specific structure of …

The spleen has a combined function of immune defence and quality control of senescent or
altered red cells. It is the first organ injured in sickle cell anaemia (SCA) with evidence of …

Exported proteins of the malaria parasite Plasmodium falciparum interact with proteins of the
erythrocyte membrane and induce substantial changes in the morphology, physiology and …

In blood vessels with luminal diameter less than 300μm, red blood cells (RBCs) which are
smaller in size and more deformable than leukocytes, migrate to the axial centre of the …

Maintaining the correct number of healthy red blood cells (RBCs) is critical for proper
oxygenation of tissues throughout the body. Therefore, RBC homeostasis is a tightly …

Malaria resulting from Plasmodium falciparum infection is a major cause of human suffering
and mortality. Red blood cell (RBC) deformability plays a major role in the pathogenesis of …

The spleen is a complex organ that is perfectly adapted to selectively filtering and destroying
senescent red blood cells (RBCs), infectious microorganisms and Plasmodium‐parasitized …