Cycles in epilepsy
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …
Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability
R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
Seizure cycles in focal epilepsy
Importance Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …
Seizure forecasting and cyclic control of seizures
Epilepsy is a unique neurologic condition characterized by recurrent seizures, where
causes, underlying biomarkers, triggers, and patterns differ across individuals. The …
causes, underlying biomarkers, triggers, and patterns differ across individuals. The …
Seizure forecasting: bifurcations in the long and winding road
To date, the unpredictability of seizures remains a source of suffering for people with
epilepsy, motivating decades of research into methods to forecast seizures. Originally, only …
epilepsy, motivating decades of research into methods to forecast seizures. Originally, only …
Cues for seizure timing
VR Rao, MG Leguia, TK Tcheng, MO Baud - Epilepsia, 2021 - Wiley Online Library
The cyclical organization of seizures in epilepsy has been described since antiquity.
However, historical explanations for seizure cycles—based on celestial, hormonal, and …
However, historical explanations for seizure cycles—based on celestial, hormonal, and …
Putative roles for homeostatic plasticity in epileptogenesis
Homeostatic plasticity allows neural circuits to maintain an average activity level while
preserving the ability to learn new associations and efficiently transmit information. This …
preserving the ability to learn new associations and efficiently transmit information. This …
Development and validation of forecasting next reported seizure using e‐diaries
DM Goldenholz, SR Goldenholz, J Romero… - Annals of …, 2020 - Wiley Online Library
Objective There are no validated methods for predicting the timing of seizures. Using
machine learning, we sought to forecast 24‐hour risk of self‐reported seizure from e‐diaries …
machine learning, we sought to forecast 24‐hour risk of self‐reported seizure from e‐diaries …
Learning to generalize seizure forecasts
MG Leguia, VR Rao, TK Tcheng, J Duun‐Henriksen… - …, 2023 - Wiley Online Library
Objective Epilepsy is characterized by spontaneous seizures that recur at unexpected times.
Nonetheless, using years‐long electroencephalographic (EEG) recordings, we previously …
Nonetheless, using years‐long electroencephalographic (EEG) recordings, we previously …
[HTML][HTML] The challenging path to developing a mobile health device for epilepsy: the current landscape and where we go from here
I Hubbard, S Beniczky, P Ryvlin - Frontiers in Neurology, 2021 - frontiersin.org
Seizure detection, and more recently seizure forecasting, represent important avenues of
clinical development in epilepsy, promoted by progress in wearable devices and mobile …
clinical development in epilepsy, promoted by progress in wearable devices and mobile …