Hypoxia and hypoxia-inducible factors in diabetes and its complications

SB Catrina, X Zheng - Diabetologia, 2021 - Springer
Hypoxia-inducible factors (HIFs) are the key regulators of oxygen homeostasis in response
to hypoxia. In diabetes, multiple tissues are hypoxic but adaptive responses to hypoxia are …

Renal protection with SGLT2 inhibitors: effects in acute and chronic kidney disease

CJ Bailey, C Day, S Bellary - Current diabetes reports, 2022 - Springer
Abstract Purpose of Review This review offers a critical narrative evaluation of emerging
evidence that sodium-glucose co-transporter-2 (SGLT2) inhibitors exert nephroprotective …

[HTML][HTML] Mechanisms leading to differential hypoxia-inducible factor signaling in the diabetic kidney: modulation by SGLT2 inhibitors and hypoxia mimetics

M Packer - American Journal of Kidney Diseases, 2021 - Elsevier
Sodium/glucose cotransporter 2 (SGLT2) inhibitors exert important renoprotective effects in
the diabetic kidney, which cannot be readily explained by their actions to lower blood …

Recent advances in medical image processing for the evaluation of chronic kidney disease

I Alnazer, P Bourdon, T Urruty, O Falou, M Khalil… - Medical Image …, 2021 - Elsevier
Assessment of renal function and structure accurately remains essential in the diagnosis
and prognosis of Chronic Kidney Disease (CKD). Advanced imaging, including Magnetic …

Hypoxia-inducible factors and diabetic kidney disease—How deep can we go?

AM Stanigut, C Pana, M Enciu, M Deacu… - International Journal of …, 2022 - mdpi.com
Diabetes is one of the leading causes of chronic kidney disease (CKD), and multiple
underlying mechanisms involved in pathogenesis of diabetic nephropathy (DN) have been …

Noninvasive assessment of diabetic kidney disease with MRI: hype or hope?

K Zhao, E Seeliger, T Niendorf… - Journal of Magnetic …, 2024 - Wiley Online Library
Owing to the increasing prevalence of diabetic mellitus, diabetic kidney disease (DKD) is
presently the leading cause of chronic kidney disease and end‐stage renal disease …

Impaired white matter integrity in infants and young children with autism spectrum disorder: What evidence does diffusion tensor imaging provide?

R Faraji, Z Ganji, SA Zamanpour, F Nikparast… - Psychiatry Research …, 2023 - Elsevier
Background Abnormal functional connections are associated with impaired white matter
tract integrity in the brain. Diffusion tensor imaging (DTI) is a promising method for …

Capability of intravoxel incoherent motion and diffusion tensor imaging to detect early kidney injury in type 2 diabetes

H Zhang, P Wang, D Shi, X Yao, Y Li, X Liu, Y Sun… - European …, 2022 - Springer
Objectives To prospectively investigate the capability of intravoxel incoherent motion (IVIM)
and conventional diffusion tensor imaging (DTI) to identify early kidney function injury in type …

Noninvasive assessment of the renal function, Oxford classification and prognostic risk stratification of IgAN by using intravoxel incoherent motion diffusion‐weighted …

P Liang, G Yuan, S Li, Y Peng, C Xu… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Immunoglobulin A nephropathy (IgAN) is the most common primary
glomerulonephritis worldwide. Oxford classification including mesangial hypercellularity (M) …

Perspectives on the role of magnetic resonance imaging (MRI) for noninvasive evaluation of diabetic kidney disease

JM Mora-Gutiérrez, MA Fernández-Seara… - Journal of Clinical …, 2021 - mdpi.com
Renal magnetic resonance imaging (MRI) techniques are currently in vogue, as they provide
in vivo information on renal volume, function, metabolism, perfusion, oxygenation, and …