ImmunoPET: concept, design, and applications
W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …
[HTML][HTML] Phosphonic acid: preparation and applications
The phosphonic acid functional group, which is characterized by a phosphorus atom
bonded to three oxygen atoms (two hydroxy groups and one P= O double bond) and one …
bonded to three oxygen atoms (two hydroxy groups and one P= O double bond) and one …
Advances in macrocyclic chelators for positron emission tomography imaging
M Li, S Wang, Q Kong, X Cheng, H Yan, Y Xing, X Lan… - View, 2023 - Wiley Online Library
In recent years, radiometals have been successfully applied to medicine because of their
breadth of decay properties and increased production and availability. Bifunctional chelators …
breadth of decay properties and increased production and availability. Bifunctional chelators …
NOTA complexes with copper (II) and divalent metal ions: kinetic and thermodynamic studies
V Kubicek, Z Bohmova, R Sevcikova, J Vanek… - Inorganic …, 2018 - ACS Publications
H3nota derivatives are among the most studied macrocyclic ligands and are widely used for
metal ion binding in biology and medicine. Despite more than 40 years of chemical research …
metal ion binding in biology and medicine. Despite more than 40 years of chemical research …
Improving the stability and inertness of Cu (II) and Cu (I) complexes with methylthiazolyl ligands by tuning the macrocyclic structure
A tacn based ligand bearing two methylthiazolyl arms (no2th) was synthesized with the aim
to find ligands forming very stable and inert complexes with Cu (II) and Cu (I) in aqueous …
to find ligands forming very stable and inert complexes with Cu (II) and Cu (I) in aqueous …
Improved conjugation, 64-cu radiolabeling, in vivo stability, and imaging using nonprotected Bifunctional macrocyclic ligands: Bis (Phosphinate) Cyclam (BPC) …
T David, V Hlinová, V Kubicek… - Journal of Medicinal …, 2018 - ACS Publications
Bifunctional derivatives of bis (phosphinate)-bearing cyclam (BPC) chelators bearing a
carboxylate, amine, isothiocyanate, azide, or cyclooctyne in the BP side chain were …
carboxylate, amine, isothiocyanate, azide, or cyclooctyne in the BP side chain were …
Copper (ii) complexes of cyclams with N-(2, 2, 2-trifluoroethyl)-aminoalkyl pendant arms as potential probes for 19 F magnetic resonance imaging
Z Kotková, F Koucký, J Kotek, I Císařová, D Parker… - Dalton …, 2023 - pubs.rsc.org
A series of Cu (II) complexes with cyclam-based ligands containing two N-(2, 2, 2-
trifluoroethyl)-aminoalkyl pendant arms in 1, 8-positions (L1: 1, 2-ethylene spacer, L2: 1, 3 …
trifluoroethyl)-aminoalkyl pendant arms in 1, 8-positions (L1: 1, 2-ethylene spacer, L2: 1, 3 …
Cyclam with a phosphinate-bis (phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides
L Pazderová, M Benešová, J Havlíčková… - Dalton …, 2022 - pubs.rsc.org
Ligands combining a bis (phosphonate) group with a macrocycle function as metal isotope
carriers for radionuclide-based imaging and for treating bone metastases associated with …
carriers for radionuclide-based imaging and for treating bone metastases associated with …
Phosphinatophenylporphyrins tailored for high photodynamic efficacy
J Hynek, M Koncošová, J Zelenka, I Křížová… - Organic & …, 2018 - pubs.rsc.org
The development of effective photosensitizers is particularly attractive for photodynamic
therapy of cancer. Three novel porphyrin photosensitizers functionalized with phosphinic …
therapy of cancer. Three novel porphyrin photosensitizers functionalized with phosphinic …
Synthesis, X-ray crystal structure, DNA/BSA binding, DNA cleavage and cytotoxicity studies of phenanthroline based copper (II)/zinc (II) complexes
Q Wang, H Mao, W Wang, H Zhu, L Dai, Y Chen… - BioMetals, 2017 - Springer
Abstract Research on copper II 1, 10-phenanththroline (phen) derivatives continues to attract
interest in the context of structure and biological properties. In this paper, two metal …
interest in the context of structure and biological properties. In this paper, two metal …