Genome protection by DNA polymerase θ

RD Wood, S Doublié - Annual review of genetics, 2022 - annualreviews.org
DNA polymerase θ (Pol θ) is a DNA repair enzyme widely conserved in animals and plants.
Pol θ uses short DNA sequence homologies to initiate repair of double-strand breaks by …

Variation is important: warranting chromatin function and dynamics by histone variants

D Jiang, F Berger - Current Opinion in Plant Biology, 2023 - Elsevier
The chromatin of flowering plants exhibits a wide range of sequence variants of the core and
linker histones. Recent studies have demonstrated that specific histone variant enrichment …

Extrachromosomal circular DNA and structural variants highlight genome instability in Arabidopsis epigenetic mutants

P Zhang, A Mbodj, A Soundiramourtty, C Llauro… - Nature …, 2023 - nature.com
Abundant extrachromosomal circular DNA (eccDNA) is associated with transposable
element (TE) activity. However, how the eccDNA compartment is controlled by epigenetic …

DAXX adds a de novo H3. 3K9me3 deposition pathway to the histone chaperone network

M Carraro, IA Hendriks, CM Hammond… - Molecular Cell, 2023 - cell.com
A multitude of histone chaperones are required to support histones from their biosynthesis
until DNA deposition. They cooperate through the formation of histone co-chaperone …

Mind the gap: epigenetic regulation of chromatin accessibility in plants

J Candela-Ferre, B Diego-Martin… - Plant …, 2024 - academic.oup.com
Chromatin plays a crucial role in genome compaction and is fundamental for regulating
multiple nuclear processes. Nucleosomes, the basic building blocks of chromatin, are …

The DNA damage response in the chromatin context: A coordinated process

J Dabin, M Mori, SE Polo - Current Opinion in Cell Biology, 2023 - Elsevier
In the cell nucleus, DNA damage signaling and repair machineries operate on a chromatin
substrate, the integrity of which is critical for cell function and viability. Here, we review …

Causes of mutation rate variability in plant genomes

D Quiroz, M Lensink, DJ Kliebenstein… - Annual Review of …, 2023 - annualreviews.org
Mutation is the source of all heritable diversity, the essential material of evolution and
breeding. While mutation rates are often regarded as constant, variability in mutation rates …

Regulation of gene editing using T-DNA concatenation

L Dickinson, W Yuan, C LeBlanc, G Thomson, S Wang… - Nature Plants, 2023 - nature.com
Transformation via Agrobacterium tumefaciens is the predominant method used to introduce
exogenous DNA into plant genomes,. Transfer DNA (T-DNA) originating from Agrobacterium …

The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated+ 1 nucleosome positioning and transcription start site determination in Arabidopsis

B Diego-Martin, J Pérez-Alemany… - Nucleic Acids …, 2022 - academic.oup.com
Eukaryotes have evolved multiple ATP-dependent chromatin remodelers to shape the
nucleosome landscape. We recently uncovered an evolutionarily conserved SWItch/Sucrose …

Deposition and eviction of histone variants define functional chromatin states in plants

AV Probst - Current Opinion in Plant Biology, 2022 - Elsevier
The organization of DNA with histone proteins into chromatin is fundamental for the
regulation of gene expression. Incorporation of different histone variants into the …