Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and has an
exceedingly low median overall survival of only 15 months. Current standard-of-care for …

Glioblastoma is the most common primary malignant brain tumor that is usually considered
fatal even with treatment. This is often a result for tumor to develop resistance. Regarding the …

Glioma is the most frequent and aggressive type of brain neoplasm, being anaplastic
astrocytoma (AA) and glioblastoma multiforme (GBM), its most malignant forms. The survival …

Despite advances in diagnostic tools and therapeutic options, treatment resistance remains
a challenge for many cancer patients. Recent studies have found evidence that autophagy …

Histone deacetylases (HDACs) inhibit the acetylation of crucial autophagy genes, thereby
deregulating autophagy and autophagic cell death (ACD) and facilitating cancer cell …

Endothelial cell dysfunction and diabetic vascular complications are intrinsically linked.
Although BDNF plays a protective role in cerebral microvascular complications caused by …

Despite the extensive efforts to find effective therapeutic strategies, glioblastoma (GBM)
remains a therapeutic challenge with dismal prognosis of survival. Over the last decade the …

Despite recent advances in multimodality therapy for glioblastoma (GB) incorporating
surgery, radiotherapy, chemotherapy and targeted therapy, the overall prognosis remains …

According to the findings of recent research, Helicobacter Pylori (H. pylori) infection is not
only the primary cause of gastric cancer (GC), but it is also linked to the spread and invasion …

Although autophagy is a well-known and extensively described cell pathway, numerous
studies have been recently interested in studying the importance of its regulation at different …